ArticleJournal of assisted reproduction and genetics2017
Assisted reproduction and risk of preterm birth in singletons by infertility diagnoses and treatment modalities: a population-based study.
Article in Journal of assisted reproduction and genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Obstetric and perinatal outcomes in pregnancies conceived with donor versus partner sperm: a systematic review and meta-analysis.Frontiers in endocrinology · 2025Pooled it
- Pathological semen parameters according to WHO and Austrian IVF funds criteria and their association with pregnancy outcomes in assisted reproduction.Wiener medizinische Wochenschrift (1946) · 2026Article
- Clomiphene Citrate Medication for Infertility and Risk of Stillbirth or Neonatal Death: A Population-based Cohort Study.The Journal of clinical endocrinology and metabolism · 2025Article
- Preterm birth in assisted reproduction: the mediating role of hypertensive disorders in pregnancy.Human reproduction (Oxford, England) · 2025Article
- Long-Term Effects of ART on the Health of the Offspring.International journal of molecular sciences · 2023Review
- The risk of prematurity in Cameroonian children born after in vitro fertilisation.Ghana medical journal · 2023Article
- Eclampsia,Translational pediatrics · 2023Article
- Association of adverse birth outcomes with in vitro fertilization after controlling infertility factors based on a singleton live birth cohort.Scientific reports · 2022Article
- Assisted Reproductive Technology Treatment, the Catalyst to Amplify the Effect of Maternal Infertility on Preterm Birth.Frontiers in endocrinology · 2022Article
- Preconception ambient temperature and preterm birth: a time-series study in rural Henan, China.Environmental science and pollution research international · 2021Article
- Observational
- A Strategic Program for Risk Assessment and Intervention to Mitigate Environmental Stressor-Related Adverse Pregnancy Outcomes in the Indian Population.Frontiers in reproductive health · 2021Review
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study is to examine the spectrum of infertility diagnoses and assisted reproductive technology (ART) treatments in relation to risk of preterm birth (PTB) in singletons.
methodsPopulation-based assisted reproductive technology surveillance data for 2000-2010 were linked with birth certificates from three states: Florida, Massachusetts, and Michigan, resulting in a sample of 4,370,361 non-ART and 28,430 ART-related singletons. Logistic regression models with robust variance estimators were used to compare PTB risk among singletons conceived with and without ART, the former grouped by parental infertility diagnoses and treatment modalities. Demographic and pregnancy factors were included in adjusted analyses.
resultsART was associated with increased PTB risk across all infertility diagnosis groups and treatment types: for conventional ART, adjusted relative risks ranged from 1.4 (95% CI 1.0, 1.9) for male infertility to 2.4 (95% CI 1.8, 3.3) for tubal ligation. Adding intra-cytoplasmic sperm injection and/or assisted hatching to conventional ART treatment did not alter associated PTB risks. Singletons conceived by mothers without infertility diagnosis and with donor semen had an increased PTB risk relative to non-ART singletons.
conclusionsPTB risk among ART singletons is increased within each treatment type and all underlying infertility diagnosis, including male infertility. Preterm birth in ART singletons may be attributed to parental infertility, ART treatments, or their combination.
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