Evidence map›Paper›PMID 28755146›Full record

ArticleEnvironmental science and pollution research international2017

Interaction of different forms of graphene with chicken embryo red blood cells.

Sławomir Jaworski, Mateusz Hinzmann, Ewa Sawosz, Marta Grodzik, Marta Kutwin, Mateusz Wierzbicki, Barbara Strojny, Krishna P Vadalasetty, Ludwika Lipińska, André Chwalibog

Abstract read
In one paragraph

Article in Environmental science and pollution research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Graphene-Based Scaffolds for Regenerative Medicine.Nanomaterials (Basel, Switzerland) · 2021
    Review
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sławomir JaworskiFaculty of Animal Science, Department of Animal Nutrition and Biotechnology, Warsaw University of Life Sciences, Ciszewskiego 8, 02-786, Warsaw, Poland. jaworski.slawek@gmail.com.
Mateusz HinzmannFaculty of Animal Science, Department of Animal Nutrition and Biotechnology, Warsaw University of Life Sciences, Ciszewskiego 8, 02-786, Warsaw, Poland.
Ewa SawoszFaculty of Animal Science, Department of Animal Nutrition and Biotechnology, Warsaw University of Life Sciences, Ciszewskiego 8, 02-786, Warsaw, Poland.
Marta GrodzikFaculty of Animal Science, Department of Animal Nutrition and Biotechnology, Warsaw University of Life Sciences, Ciszewskiego 8, 02-786, Warsaw, Poland.
Marta KutwinFaculty of Animal Science, Department of Animal Nutrition and Biotechnology, Warsaw University of Life Sciences, Ciszewskiego 8, 02-786, Warsaw, Poland.
Mateusz WierzbickiFaculty of Animal Science, Department of Animal Nutrition and Biotechnology, Warsaw University of Life Sciences, Ciszewskiego 8, 02-786, Warsaw, Poland.
Barbara StrojnyFaculty of Animal Science, Department of Animal Nutrition and Biotechnology, Warsaw University of Life Sciences, Ciszewskiego 8, 02-786, Warsaw, Poland.
Krishna P VadalasettyDepartment of Veterinary Clinical and Animal Sciences, University of Copenhagen, Copenhagen, Denmark.
Ludwika LipińskaInstitute of Electronic Materials Technology, Warsaw, Poland.
André ChwalibogDepartment of Veterinary Clinical and Animal Sciences, University of Copenhagen, Copenhagen, Denmark.

Funding

Narodowe Centrum Nauki NCN 2013/09/N/NZ9/01898
6 · The paper itself

Abstract

With the rapid development of graphene synthesis and functionalization approaches, graphene and its related derivatives have shown great potential in many applications in material science, including biomedical applications. Several in vitro and in vivo studies clearly showed no definitive risks, while others have indicated that graphene might become health hazards. In this study, we explore the biocompatibility of graphene-related materials with chicken embryo red blood cells (RBC). The hemolysis assay was employed to evaluate the in vitro blood compatibility of reduced graphene, graphene oxide, and reduced graphene oxide, because these materials have recently been used for biomedical applications, including injectable graphene-related particles. This study investigated structural damage, ROS production and hemolysis of chicken embryo red blood cells. Different forms of graphene, when incubated with chicken embryo RBC, were harmful to cell structure and induced hemolysis.

Indexed as

Materials TestingAnimalsChick EmbryoChickensErythrocyte CountErythrocytesGraphiteHemolysisOxidesGraphiteOxidesGrapheneRed blood cellsToxicity

Identifiers

PMID28755146
PMCPMC5591802

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.