Evidence map›Paper›PMID 28755129›Full record

ArticleInflammopharmacology2018

Acid-gastric antisecretory effect of the ethanolic extract from Arctium lappa L. root: role of H

Luisa Mota da Silva, Ligia de Moura Burci, Sandra Crestani, Priscila de Souza, Rita de Cássia Melo Vilhena de Andrade Fonseca da Silva, Nessana Dartora, Lauro Mera de Souza, Thales Ricardo Cipriani, José Eduardo da Silva-Santos, Eunice André and 1 more

Abstract read
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In one paragraph

Article in Inflammopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Gastroprotective activity of (Pharmaceutical biology · 2022
    Article
  6. First Evidence of Gastroprotection byMolecules (Basel, Switzerland) · 2022
    Article
  7. Plants (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Luisa Mota da SilvaDepartamento de Farmacologia, Setor de Ciências Biológicas, Universidade Federal do Paraná, Curitiba, PR, Brazil. lu.isamota@hotmail.com.ORCID http://orcid.org/0000-0001-5329-7301
Ligia de Moura BurciDepartamento de Farmacologia, Setor de Ciências Biológicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Sandra CrestaniDepartamento de Bioquímica, Setor de Ciências Biológicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Priscila de SouzaDepartamento de Farmacologia, Setor de Ciências Biológicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Rita de Cássia Melo Vilhena de Andrade Fonseca da SilvaDepartamento de Farmacologia, Setor de Ciências Biológicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Nessana DartoraDepartamento de Bioquímica, Setor de Ciências Biológicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Lauro Mera de SouzaDepartamento de Bioquímica, Setor de Ciências Biológicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Thales Ricardo CiprianiDepartamento de Bioquímica, Setor de Ciências Biológicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
José Eduardo da Silva-SantosLaboratório de Biologia Cardiovascular, Departmento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
Eunice AndréDepartamento de Farmacologia, Setor de Ciências Biológicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Maria Fernanda de Paula WernerDepartamento de Farmacologia, Setor de Ciências Biológicas, Universidade Federal do Paraná, Curitiba, PR, Brazil. mfernanda.werner@ufpr.br.
Universidade Federal do Paraná · BRUniversidade do Vale do Itajaí · BRUniversidade Federal de Santa Catarina · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArctium lappa L., popularly known as burdock, is a medicinal plant used worldwide. The antiulcer and gastric-acid antisecretory effects of ethanolic extract from roots of Arctium lappa (EET) were already demonstrated. However, the mechanism by which the extract reduces the gastric acid secretion remains unclear. Therefore, this study was designed to evaluate the antisecretory mode of action of EET. MATERIALS AND

methodsThe effects of EET on H

resultsThe incubation with EET (1000 µg/ml) partially inhibited H

conclusionOur results reinforce the gastric antisecretory properties of preparations obtained from Arctium lappa, and indicate that the mechanisms involved in EET antisecretory effects include a moderate reduction of the H

Indexed as

Adenosine TriphosphatasesAnimalsAnti-Ulcer AgentsArctiumCalciumCholinergic AgentsEthanolFemaleGastric AcidGastric MucosaPlant ExtractsPlant RootsPlants, MedicinalRatsRats, WistarAdenosine TriphosphatasesAnti-Ulcer AgentsCalciumCholinergic AgentsEthanolPlant ExtractsAcetylcholineBurdockCalciumGastric fundusH+, K+-ATPasePylorus ligation

Identifiers

PMID28755129
OpenAlexW2740208757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.