ArticleScientific reports2017
Transitions between classes of neuronal excitability and bifurcations induced by autapse.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 80 citations in OpenAlex.
- [Effect of repeated transcranial magnetic stimulation on excitability of glutaminergic neurons and gamma-aminobutyric neurons in mouse hippocampus].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025Article
- [Analysis of nerve excitability in the dentate gyrus of the hippocampus in cerebral ischaemia-reperfusion mice].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024Article
- Three-dimensional memristive Morris-Lecar model with magnetic induction effects and its FPGA implementation.Cognitive neurodynamics · 2023Article
- Repetitive transcranial magnetic stimulation enhances the neuronal excitability of mice by regulating dynamic characteristics of Granule cells' Ion channels.Cognitive neurodynamics · 2023Article
- [Effects of repetitive transcranial magnetic stimulation on neuronal excitability and ion channels in hindlimb unloading mice].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023Article
- Complex dynamics of hair bundle of auditory nervous system (I): spontaneous oscillations and two cases of steady states.Cognitive neurodynamics · 2022Article
- Canard solutions in neural mass models: consequences on critical regimes.Journal of mathematical neuroscience · 2021Article
- Excitability and Threshold Mechanism for Enhanced Neuronal Response Induced by Inhibition Preceding Excitation.Neural plasticity · 2021Article
- Influence of Autapses on Synchronization in Neural Networks With Chemical Synapses.Frontiers in systems neuroscience · 2020Article
- Dynamical Mechanism of Hyperpolarization-Activated Non-specific Cation Current Induced Resonance and Spike-Timing Precision in a Neuronal Model.Frontiers in cellular neuroscience · 2018Article
- Response of Electrical Activity in an Improved Neuron Model under Electromagnetic Radiation and Noise.Frontiers in computational neuroscience · 2017Article
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2 authors at 1 institution in 1 country.
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Abstract
Neuronal excitabilities behave as the basic and important dynamics related to the transitions between firing and resting states, and are characterized by distinct bifurcation types and spiking frequency responses. Switches between class I and II excitabilities induced by modulations outside the neuron (for example, modulation to M-type potassium current) have been one of the most concerning issues in both electrophysiology and nonlinear dynamics. In the present paper, we identified switches between 2 classes of excitability and firing frequency responses when an autapse, which widely exists in real nervous systems and plays important roles via self-feedback, is introduced into the Morris-Lecar (ML) model neuron. The transition from class I to class II excitability and from class II to class I spiking frequency responses were respectively induced by the inhibitory and excitatory autapse, which are characterized by changes of bifurcations, frequency responses, steady-state current-potential curves, and nullclines. Furthermore, we identified codimension-1 and -2 bifurcations and the characteristics of the current-potential curve that determine the transitions. Our results presented a comprehensive relationship between 2 classes of neuronal excitability/spiking characterized by different types of bifurcations, along with a novel possible function of autapse or self-feedback control on modulating neuronal excitability.
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