ArticleThe EMBO journal2017
Recombination at subtelomeres is regulated by physical distance, double-strand break resection and chromatin status.
Article in The EMBO journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 53 citations in OpenAlex.
- Ctf18-dependent localization of interstitial telomeric sequence to nuclear pore complexes prevents chromosome fragility.Nucleic acids research · 2026Article
- DNA shape and epigenomics distinguish the mechanistic origin of human genomic structural variations.Nucleic acids research · 2025Article
- Cohesin complex oligomerization maintains end-tethering at DNA double-strand breaks.Nature cell biology · 2025Article
- In vivo tracking of functionally tagged Rad51 unveils a robust strategy of homology search.Nature structural & molecular biology · 2023Article
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- Comprehensive analysis of cis- and trans-acting factors affecting ectopic Break-Induced Replication.PLoS genetics · 2022Article
- Review
- Sir3 heterochromatin protein promotes non-homologous end joining by direct inhibition of Sae2.The EMBO journal · 2022Article
- Cohesin regulates homology search during recombinational DNA repair.Nature cell biology · 2021Article
- Architecture and evolution of subtelomeres in the unicellular green alga Chlamydomonas reinhardtii.Nucleic acids research · 2021Article
- A new assay capturing chromosome fusions shows a protection trade-off at telomeres and NHEJ vulnerability to low-density ionizing radiation.Nucleic acids research · 2021Article
- Empirical evidence for epigenetic inheritance driving evolutionary adaptation.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Sir3 mediates long-range chromosome interactions in budding yeast.Genome research · 2021Article
- Single molecule microscopy reveals key physical features of repair foci in living cells.eLife · 2021Article
- Telomere Roles in Fungal Genome Evolution and Adaptation.Frontiers in genetics · 2021Article
- Collaborations between chromatin and nuclear architecture to optimize DNA repair fidelity.DNA repair · 2021Review
- The Secret Life of Chromosome Loops upon DNA Double-Strand Break.Journal of molecular biology · 2020Review
- Inference and analysis of population-specific fine-scale recombination maps across 26 diverse human populations.Science advances · 2019Article
- Subtelomeres are fast-evolving regions of theMicrobial genomics · 2019Article
- Discovery and Evolution of New Domains in Yeast Heterochromatin Factor Sir4 and Its Partner Esc1.Genome biology and evolution · 2019Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Homologous recombination (HR) is a conserved mechanism that repairs broken chromosomes via intact homologous sequences. How different genomic, chromatin and subnuclear contexts influence HR efficiency and outcome is poorly understood. We developed an assay to assess HR outcome by gene conversion (GC) and break-induced replication (BIR), and discovered that subtelomeric double-stranded breaks (DSBs) are preferentially repaired by BIR despite the presence of flanking homologous sequences. Overexpression of a silencing-deficient
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