ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2017
Lung Function and Incident Kidney Disease: The Atherosclerosis Risk in Communities (ARIC) Study.
Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 51 citations in OpenAlex.
- Significant Spirometric Transitions and Preserved Ratio Impaired Spirometry Among Ever Smokers.Chest · 2022Trial
- Lung function impairment and risk of sepsis and sepsis-related mortality: a large cohort study with over 310,000 participants.Science China. Life sciences · 2026Article
- Role of Lung Function, Chronic Obstructive Pulmonary Disease on Hearing Impairment: Evidence for Causal Effects and Clinical Implications.Audiology research · 2025Article
- Preserved ratio impaired spirometry, airflow obstruction, and their trajectories in relationship to chronic kidney disease: a prospective cohort study.Scientific reports · 2025Article
- Association between measures of kidney function and preserved ratio impaired spirometry in diabetes: NHANES 2007-2012.BMJ open · 2024Article
- Association between pulmonary function and rapid kidney function decline: a longitudinal cohort study from CHARLS.BMJ open respiratory research · 2024Article
- Trend and heterogeneity in forced vital capacity among Chinese students during 1985-2019: results from Chinese National Survey on Students' Constitution and Health.Respiratory research · 2023Article
- Nontraditional Risk Factors for Progression Through Chronic Kidney Disease Risk Categories: The Coronary Artery Risk Development in Young Adults Study.The American journal of medicine · 2023Article
- Lung Dysfunction and Chronic Kidney Disease: A Complex Network of Multiple Interactions.Journal of personalized medicine · 2023Review
- Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission.Lancet (London, England) · 2022Review
- Is There an Association Between Chronic Obstructive Pulmonary Disease and Chronic Renal Failure?Cureus · 2022Review
- Echocardiographic measures and subsequent decline in kidney function in older adults: the Atherosclerosis Risk in Communities Study.European heart journal. Cardiovascular Imaging · 2022Article
- Distinguishing causation from genetic correlation in a Mendelian randomisation framework.The European respiratory journal · 2021Article
- Longitudinal change in lung function and subsequent risks of cardiovascular events: evidence from four prospective cohort studies.BMC medicine · 2021Article
- Article
- Relationship between pulmonary function and albuminuria in type 2 diabetic patients with preserved renal function.BMC endocrine disorders · 2020Article
- Low lung function and the risk of incident chronic kidney disease in the Malmö Preventive Project cohort.BMC nephrology · 2020Article
- Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population.Metabolites · 2019Article
- Reduced forced vital capacity is independently associated with ethnicity, metabolic factors and respiratory symptoms in a Caribbean population: a cross-sectional study.BMC pulmonary medicine · 2019Article
- Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundReduced lung function is associated with clinical outcomes such as cardiovascular disease. However, little is known about its association with incident end-stage renal disease (ESRD) and chronic kidney disease (CKD). STUDY
designProspective cohort study. SETTING &
participants14,946 participants aged 45 to 64 years at baseline (1987-1989) in the Atherosclerosis Risk in Communities (ARIC) Study (45.0% men and 25.2% black), with follow-up through 2012. PREDICTORS: Race- and sex-specific quartiles of percent-predicted forced vital capacity (FVC) and the proportion of forced expiratory volume in 1 second of expiration to FVC (FEV OUTCOMES: Incident ESRD (defined here as renal replacement therapy or death due to CKD) as the primary outcome and incident CKD (defined here as ESRD, ≥25% decline in estimated glomerular filtration rate to a level <60mL/min/1.73m
resultsDuring a median follow-up of 23.6 years, 526 (3.5%) participants developed ESRD. After adjusting for potential confounders, the cause-specific HR of incident ESRD for the lowest (vs highest) quartile was 1.72 (95% CI, 1.31-2.26) for percent-predicted FVC and 1.33 (95% CI, 1.03-1.73) for FEV LIMITATIONS: Limited number of participants with moderate/severe lung dysfunction and spirometry only at baseline.
conclusionsReduced lung function, particularly lower percent-predicted FVC, is independently associated with CKD progression. Our findings suggest a potential pathophysiologic contribution of reduced lung function to the development of CKD and a need for monitoring kidney function in persons with reduced lung function.
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