Evidence map›Paper›PMID 28754339›Full record

ArticleThe Journal of investigative dermatology2017

IL-1 Receptor-Knockout Mice Develop Epidermal Cysts and Show an Altered Innate Immune Response after Exposure to UVB Radiation.

Nikhil N Kulkarni, Christopher A Adase, Ling-Juan Zhang, Andrew W Borkowski, Fengwu Li, James A Sanford, Daniel J Coleman, Carlos Aguilera, Arup K Indra, Richard L Gallo

Open access · greenAbstract read
In one paragraph

Article in The Journal of investigative dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. The Influence of Circadian Rhythms on DNA Damage Repair in Skin Photoaging.International journal of molecular sciences · 2024
    Review
  3. Article
  4. Review
  5. Selective inhibition of PKR by C16 accelerates diabetic wound healing by inhibiting NALP3 expression in mice.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Article
  6. The Role of Probiotics in Skin Photoaging and Related Mechanisms: A Review.Clinical, cosmetic and investigational dermatology · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Nikhil N KulkarniDepartment of Dermatology, University of California, San Diego, California, USA.
Christopher A AdaseDepartment of Dermatology, University of California, San Diego, California, USA.
Ling-Juan ZhangDepartment of Dermatology, University of California, San Diego, California, USA.
Andrew W BorkowskiDepartment of Dermatology, University of California, San Diego, California, USA.
Fengwu LiDepartment of Dermatology, University of California, San Diego, California, USA.
James A SanfordDepartment of Dermatology, University of California, San Diego, California, USA.
Daniel J ColemanDepartment of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon, USA; Molecular and Cellular Biology Program, Oregon State University, Corvallis, Oregon, USA.
Carlos AguileraDepartment of Dermatology, University of California, San Diego, California, USA.
Arup K IndraDepartment of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon, USA; Molecular and Cellular Biology Program, Oregon State University, Corvallis, Oregon, USA; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon, USA; Linus Pauling Science Center, Oregon State University, Corvallis, Oregon, USA; Department of Dermatology, Oregon Health and Science University, Portland, Oregon, USA; Knight Cancer Institute, Portland, Oregon, USA.
Richard L GalloDepartment of Dermatology, University of California, San Diego, California, USA. Electronic address: rgallo@ucsd.edu.
University of California San Diego · USOregon State University · US

Funding

Cathelicidins in Skin ImmunityR01AI052453 · NIAID · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI GALLO, RICHARD L, NIZET, VICTOR · 2002 to 2017
$5.3M
Cathelicidin in Skin ImmunityR37AI052453 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Richard L Gallo, Victor Nizet · 2019 to 2026
$4.6M
Training in the Molecular Basis of Skin/Mucosa PathobiologyT32CA106195 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI KULESZ-MARTIN, MOLLY F. · 2004 to 2018
$3.8M
Proteolysis and Skin AntimicrobialsR01AR052728 · NIAMS · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI GALLO, RICHARD L · 2006 to 2015
$3.3M
Skin Barrier and the MicrobiomeR01AR064781 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GALLO, RICHARD L, HATA, TISSA R · 2014 to 2018
$1.8M
Mechanism of keratinocyte RXRalpha mediated melanoma skin cancer developmentR01ES016629 · NIEHS · OREGON STATE UNIVERSITY · PI INDRA, ARUP K. · 2009 to 2013
$1.6M
UCSD Dermatologist Investigator Training ProgramT32AR062496 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GALLO, RICHARD L · 2012 to 2016
$982k
NCI NIH HHS T32 CA106195NIAID NIH HHS R01 AI052453NIAID NIH HHS R37 AI052453NIAMS NIH HHS R01 AR052728NIAMS NIH HHS R01 AR064781NIAMS NIH HHS T32 AR062496NIEHS NIH HHS R01 ES016629
6 · The paper itself

Abstract

In this study, we observed that mice lacking the IL-1 receptor (IL-1R) (IL1r

Indexed as

Gene Expression RegulationAnimalsBiopsy, NeedleBlotting, WesternCells, CulturedDisease Models, AnimalDNA DamageEpidermal CystFemaleImmunity, InnateImmunohistochemistryKeratinocytesMiceMice, Inbred C57BLMice, KnockoutRandom AllocationReceptors, Interleukin

Identifiers

PMID28754339
PMCPMC5800765
OpenAlexW2737324922

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.