ArticleMolecules (Basel, Switzerland)2017
Effects of Chlorhexidine-Encapsulated Mesoporous Silica Nanoparticles on the Anti-Biofilm and Mechanical Properties of Glass Ionomer Cement.
Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of propolis-modified glass ionomer cement on antimicrobial activity and physico-mechanical properties: a systematic review.Odontology · 2026Pooled it
- Caries Management with Non-Metallic Nanomaterials: A Systematic Review.International journal of nanomedicine · 2022Pooled it
- Gel Containing Catechin and Mesoporous Silica Nanoparticles for Protecting Root Dentin Against Erosion: An In Situ Study.Microscopy research and technique · 2025Trial
- Review
- Evaluation of Experimental Nanocomposite-Based Solution and Dentifrice for Reducing Dental Erosive Wear.Brazilian dental journal · 2026Article
- Experimental glass ionomer cement modified by the incorporation of nanoselenuim: antibacterial activity, cytocompatibility and compressive strength.BMC oral health · 2025Article
- Investigation of the Combined Impact of Zinc Oxide Nanoparticles and Bacterial Cellulose Nanocrystals on the Bond Strength to Dentin and Fracture Resistance of Resin-Modified Glass Ionomer Cement in Primary Molars.Clinical and experimental dental research · 2025Article
- Dual-Mode Antibacterial Orthodontic Composite: Contact-Killing QACs and Sustained CHX Release via Large-Pore Mesoporous Silica Nanoparticles.International journal of molecular sciences · 2025Article
- Assessment of the Antimicrobial Properties of Mesoporous Zinc Oxide Nanoparticles AgainstInternational journal of dentistry · 2025Article
- Glass Ionomer Cements with Halloysite-CHX: Physicochemical Properties, Antimicrobial Activity, Cell Viability.Brazilian dental journal · 2025Article
- Evaluating mesoporous zinc oxide nanoparticles for dentin pretreatment: Synthesis, characterization, and bond strength performance with a universal adhesive.Dental research journal · 2025Article
- Impact of Mesoporous Zinc Oxide Nanoparticles on Diametral Tensile Strength and Flexural Strength of Resin-Modified Glass Ionomer Cement: An In-Vitro Study.Frontiers in dentistry · 2025Article
- Examining the Impact of Mesoporous Zinc Oxide Nanoparticle Inclusion on the Surface Microhardness and Roughness of Resin-Modified Glass Ionomer Cement: An In Vitro Analysis.International journal of dentistry · 2025Article
- The effect of mesoporous silica doped with silver nanoparticles on glass ionomer cements; physiochemical, mechanical and ion release analysis.BMC oral health · 2024Article
- Effect of Modified Bioceramic Mineral Trioxide Aggregate Cement with Mesoporous Nanoparticles on Human Gingival Fibroblasts.Current issues in molecular biology · 2024Article
- Synthesis and characterization of mesoporous zinc oxide nanoparticles and evaluation of their biocompatibility in L929 fibroblasts.Clinical and experimental dental research · 2024Article
- Multifunctional mesoporous silica nanoparticles for biomedical applications.Signal transduction and targeted therapy · 2023Review
- One-Pot Preparation of Cetylpyridinium Chloride-Containing Nanoparticles for Biofilm Eradication.ACS applied bio materials · 2023Article
- The application of mesoporous silica nanoparticles as a drug delivery vehicle in oral disease treatment.Frontiers in cellular and infection microbiology · 2023Review
- Ceramic Nanomaterials in Caries Prevention: A Narrative Review.Nanomaterials (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the primary causes for the failure of glass ionomer cement (GIC) is secondary caries. To enhance the anti-microbial performance of GIC without affecting its mechanical properties, chlorhexidine (CHX) was encapsulated in expanded-pore mesoporous silica nanoparticles (pMSN) to synthesize CHX@pMSN. CHX@pMSN was added at three mass fractions (1%, 5%, and 10% (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.