Evidence map›Paper›PMID 28753474›Full record

ArticleNeurobiology of aging2017

Age-related changes in envelope-following responses at equalized peripheral or central activation.

Jesyin Lai, Alexandra L Sommer, Edward L Bartlett

Abstract read
In one paragraph

Article in Neurobiology of aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  7. Review
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  10. Review
  11. Temporal Coding of Single Auditory Nerve Fibers Is Not Degraded in Aging Gerbils.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jesyin LaiDepartment of Biological Sciences, Purdue University, West Lafayette, IN, USA.
Alexandra L SommerDepartment of Biological Sciences, Purdue University, West Lafayette, IN, USA.
Edward L BartlettDepartment of Biological Sciences and the Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA. Electronic address: ebartle@purdue.edu.

Funding

Measurement and modeling of central auditory processing in aged animalsR01DC011580 · NIDCD · PURDUE UNIVERSITY · PI BARTLETT, EDWARD · 2012 to 2016
$1.7M
NIDCD NIH HHS R01 DC011580
6 · The paper itself

Abstract

Previous work has debated about the comparisons of hearing abilities faced with alterations in hearing thresholds and evoked potentials between groups following acoustic trauma- or age-related changes. This study compares envelope-following responses (EFRs) of young and aged rats when sound levels were matched according to (1) wave I amplitudes of auditory brainstem responses (ABRs) elicited by 8-kHz tones or (2) EFR amplitudes evoked by sinusoidally amplitude-modulated (SAM) tones at 100% depth. Matched wave I amplitudes across age corresponded to approximately 20-dB sound level differences. For matched wave I, no age-related differences were observed in wave V amplitudes. However, EFRs recorded in silence were enhanced with aging at 100% but not at 25% depth, consistent with enhanced central gain in aging. For matched EFRs, there were no age-related differences in EFRs of amplitude modulation (AM) depth and AM frequency processing. These results suggest novel, objective measures beyond threshold to compensate for differences in auditory nerve activation and to differentiate peripheral and central contributions of EFRs.

Indexed as

Acoustic StimulationAgingAnimalsAuditory PerceptionAuditory ThresholdCochlear NerveEvoked Potentials, AuditoryEvoked Potentials, Auditory, Brain StemFemaleHearingMaleRats, Inbred F344AgingAmplitude modulationEnvelope codingEnvelope-following responses

Identifiers

PMID28753474
PMCPMC5581704

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.