Evidence map›Paper›PMID 28753230›Full record

Trial reportCancer2017

A centralized mailed program with stepped increases of support increases time in compliance with colorectal cancer screening guidelines over 5 years: A randomized trial.

Beverly B Green, Melissa L Anderson, Andrea J Cook, Jessica Chubak, Sharon Fuller, Richard T Meenan, Sally W Vernon

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. A Systematic Review of Repeat Fecal Occult Blood Tests for Colorectal Cancer Screening.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
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  12. What Multilevel Interventions Do We Need to Increase the Colorectal Cancer Screening Rate to 80%?Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2021
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  16. Methodologic Considerations in Calculating and Analyzing Proportion of Time Covered as a Measure of Longitudinal Cancer Screening Adherence.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Beverly B GreenKaiser Permanente Washington, Seattle, Washington.ORCID http://orcid.org/0000-0003-3040-3436
Melissa L AndersonKaiser Permanente Health Research Institute, Seattle, Washington.
Andrea J CookUniversity of Washington School of Public Health, Seattle, Washington.
Jessica ChubakKaiser Permanente Health Research Institute, Seattle, Washington.
Sharon FullerKaiser Permanente Health Research Institute, Seattle, Washington.
Richard T MeenanCenter for Health Research, Kaiser Permanente Northwest, Portland, Oregon.
Sally W VernonUniversity of Texas School of Public Health, Houston, Texas.

Funding

Systems of Support (SOS) to Increase Colon Cancer Screening and Follow-upR01CA121125 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI GREEN, BEVERLY BETH · 2007 to 2017
$8.0M
NCI NIH HHS R01 CA121125
6 · The paper itself

Abstract

backgroundScreening over many years is required to optimize reductions in colorectal cancer (CRC) mortality. However, no prior trials have compared strategies for obtaining long-term adherence.

methodsSystems of Support to Increase Colorectal Cancer Screening and Follow-Up was implemented in an integrated health care organization in Washington State. Between 2008 and 2009, 4675 individuals aged 50 to 74 years were randomized to receive the usual care (UC), which included clinic-based strategies to increase CRC screening (arm 1), or, in years 1 and 2, mailings with a call-in number for colonoscopy and mailed fecal tests (arm 2), mailings plus brief telephone assistance (arm 3), or mailings and assistance plus nurse navigation (arm 4). Active-intervention subjects (those in arms 2, 3, and 4 combined) who were still eligible for CRC screening were randomized to mailings being stopped or continued in years 3 and 5. The time in compliance with CRC screening over 5 years was compared for persons assigned to any intervention and persons assigned to UC. Screening tests contributed time on the basis of national guidelines for screening intervals (fecal tests annually, sigmoidoscopy every 5 years, and colonoscopy every 10 years).

resultsAll participants contributed data, but they were censored at disenrollment, death, the age of 76 years, or a diagnosis of CRC. Compared with UC participants, intervention participants had 31% more adjusted covered time over 5 years (incidence rate ratio, 1.31; 95% confidence interval, 1.25-1.37; covered time, 47.5% vs 62.1%). Fecal testing accounted for almost all additional covered time.

conclusionsIn a health care organization with clinic-based activities to increase CRC screening, a centralized program led to increased CRC screening adherence over 5 years. Longer term data on screening adherence and its impact on CRC outcomes are needed. Cancer 2017;123:4472-80. © 2017 American Cancer Society.

Indexed as

Patient CompliancePostal ServicePractice Guidelines as TopicReminder SystemsAgedColonoscopyColorectal NeoplasmsEarly Detection of CancerFemaleHumansMaleMass ScreeningMiddle AgedOccult BloodTelephoneTime Factorsadherencecolorectal cancerhealth servicesprevention and controlscreening

Identifiers

PMID28753230
PMCPMC5673524

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.