ArticlePharmacoepidemiology and drug safety2017
Use of direct oral anticoagulants in patients with atrial fibrillation in Scotland: Applying a coherent framework to drug utilisation studies.
Article in Pharmacoepidemiology and drug safety, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Delay and Pay? Healthcare Costs Associated with Late Oral Anti-coagulant Prescribing in People with Atrial Fibrillation.PharmacoEconomics · 2024Article
- Evaluating the effect of inequalities in oral anti-coagulant prescribing on outcomes in people with atrial fibrillation.European heart journal open · 2024Article
- Pharmacoepidemiology: An Overview.Journal of clinical medicine · 2023Review
- Article
- Article
- Factors associated with primary nonadherence to newly initiated direct oral anticoagulants in patients with nonvalvular atrial fibrillation.Journal of managed care & specialty pharmacy · 2021Observational
- World Heart Federation Roadmap on Atrial Fibrillation - A 2020 Update.Global heart · 2021Review
- Use of non-vitamin K antagonist oral anticoagulants in Colombia: A descriptive study using a national administrative healthcare database.Pharmacoepidemiology and drug safety · 2021Article
- Adherence to Direct Oral Anticoagulants in Patients With Non-Valvular Atrial Fibrillation: A Cross-National Comparison in Six European Countries (2008-2015).Frontiers in pharmacology · 2021Article
- Real-world evaluation of the impact of statin intensity on adherence and persistence to therapy: A Scottish population-based study.British journal of clinical pharmacology · 2020Article
- Adherence and the Moral Construction of the Self: A Narrative Analysis of Anticoagulant Medication.Qualitative health research · 2020Article
- Persistence, effectiveness and safety of dabigatran in "real-world" Chinese patients with nonvalvular atrial fibrillation.Heart and vessels · 2020Observational
- Improving prescribing through big data approaches-Ten years of the Scottish Prescribing Information System.British journal of clinical pharmacology · 2020Review
- Persistence of oral anticoagulant treatment for atrial fibrillation in the Netherlands: A surveillance study.Research and practice in thrombosis and haemostasis · 2020Article
- Adherence and persistence to direct oral anticoagulants in atrial fibrillation: a population-based study.Heart (British Cardiac Society) · 2020Observational
- Article
- Incidence of direct oral anticoagulant use in patients with nonvalvular atrial fibrillation and characteristics of users in 6 European countries (2008-2015): A cross-national drug utilization study.British journal of clinical pharmacology · 2019Article
- Reducing Stroke Risk in Atrial Fibrillation: Adherence to Guidelines Has Improved, but Patient Persistence with Anticoagulant Therapy Remains Suboptimal.Korean circulation journal · 2019Review
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
purposeTo report the use of direct oral anticoagulants (DOACs) for stroke prevention in patients with atrial fibrillation in Scotland and advocate the standardisation of drug utilisation research methods.
methodsRetrospective cohort study using linked administrative data. Patients included those with a diagnosis of atrial fibrillation (confirmed in hospital) who received a first prescription for a DOAC (dabigatran, rivaroxaban, or apixaban) from September 2011 to June 2014. Drug utilisation measures included discontinuation, persistence, and adherence.
resultsA total of 5398 patients (mean CHA
conclusionsIn Scotland, adherence to DOAC treatment was good, and switching from DOAC to warfarin was low. However, discontinuation and persistence rates were variable-although treatment interruptions were often temporary. To decrease the inconsistencies in drug utilisation methods and facilitate meaningful study comparison, the use of a coherent framework-using a combination of discontinuation, persistence, and adherence-and the standardisation of measurements is advocated.
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