Evidence map›Paper›PMID 28752577›Full record

SynthesisHealth expectations : an international journal of public participation in health care and health policy2018

Extent, quality and impact of patient and public involvement in antimicrobial drug development research: A systematic review.

David Evans, Emma Bird, Andy Gibson, Sally Grier, Teh Li Chin, Margaret Stoddart, Alasdair MacGowan, North Bristol Microbiology Patient Panel

Abstract readSystematic Review
In one paragraph

Synthesis in Health expectations : an international journal of public participation in health care and health policy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Extent, quality and impact of patient and public involvement in antimicrobial drug development research: A systematic review.Health expectations : an international journal of public participation in health care and health policy · 2018
    Pooled it
  4. Perspectives of researchers and clinicians on patient and public involvement (PPI) in preclinical spinal cord research: An interview study.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
  5. Applying Patient and Public Involvement in preclinical research: A co-created scoping review.Health expectations : an international journal of public participation in health care and health policy · 2022
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Evaluating the "return on patient engagement initiatives" in medicines research and development: A literature review.Health expectations : an international journal of public participation in health care and health policy · 2020
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David EvansDepartment of Health and Social Sciences, University of the West of England, Bristol, UK.ORCID 0000-0001-6961-7031
Emma BirdDepartment of Health and Social Sciences, University of the West of England, Bristol, UK.
Andy GibsonDepartment of Health and Social Sciences, University of the West of England, Bristol, UK.
Sally GrierDepartment of Infection Sciences, Southmead Hospital, Bristol, UK.
Teh Li ChinDepartment of Infection Sciences, Southmead Hospital, Bristol, UK.
Margaret StoddartDepartment of Infection Sciences, Southmead Hospital, Bristol, UK.
Alasdair MacGowanDepartment of Infection Sciences, Southmead Hospital, Bristol, UK.
North Bristol Microbiology Patient Panel

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatient and public involvement (PPI) is increasingly recognized as bringing a range of benefits to clinical and health services research. Recent systematic reviews have identified and synthesized many benefits (eg higher recruitment rates) and some costs (eg extra time need). Much of the literature focuses on PPI in long-term conditions rather than more acute health care in which the majority of microbiological research is undertaken.

objectivesThe aim was to identify the extent, quality and impact of PPI in antimicrobial drug development research. Objectives were to identify any relevant reporting of PPI in antimicrobial research; appraise the quality of reporting on PPI using recognized PPI reporting and critical appraisal tools; and extract and synthesize data on the impact of PPI. SEARCH STRATEGY: A systematic review was undertaken with a search strategy based on four word groups (PPI, patients, antimicrobial drug development and outcomes). Eight online databases were searched. INCLUSION CRITERIA: English language publication, publication between 1996 and 2016 and studies describing PPI in antimicrobial drug development research. MAIN

resultsNo studies were found through online searching that met the search strategy and inclusion criteria. One relevant protocol paper with a brief mention of PPI was identified through expert recommendation. Commentary papers recommending PPI were identified through website searching and expert opinion. DISCUSSION AND

conclusionsDespite strong policy guidance encouraging PPI at the international and national levels, and anecdotal accounts of PPI taking place, evidence for the extent, quality and impact of PPI in antimicrobial drug development research has not yet appeared in the peer-reviewed literature.

Indexed as

Anti-Infective AgentsDrug DevelopmentPatient ParticipationHealth Services ResearchHumansAnti-Infective Agentsantimicrobial drug developmentmicrobiologypatient and public involvement

Identifiers

PMID28752577
PMCPMC5750755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.