ArticleEchocardiography (Mount Kisco, N.Y.)2017
A preliminary comparison of two-dimensional speckle tracking echocardiography and pressure-volume loop analysis in patients with Fontan physiology: The role of ventricular morphology.
Article in Echocardiography (Mount Kisco, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 21 citations in OpenAlex.
- Ejection Fraction-Related Differences in Left Ventricular and Atrial Strain Indices Among Pediatric Fontan Circulation with Systemic Left Ventricle Morphology.Diagnostics (Basel, Switzerland) · 2026Article
- Myocardial and Atrial Strain Profiles in Pediatric Fontan Patients with Single Left Ventricle Using Two-Dimensional Speckle-Tracking Echocardiography: A Case-Control Study.Journal of clinical medicine · 2025Article
- Transthoracic echocardiographic assessment of ventricular function in functional single ventricle: a comprehensive review.Cardiovascular ultrasound · 2025Review
- Right Ventricle-Pulmonary Artery Coupling in Patients Undergoing Cardiac Interventions.Current cardiology reports · 2024Review
- Heart Failure with Preserved Ejection Fraction in Children.Pediatric cardiology · 2023Review
- Management of circulatory failure after Fontan surgery.Frontiers in pediatrics · 2022Review
- Clinical Applications of Pressure-Volume Assessment in Congenital Heart Disease.Journal of the Society for Cardiovascular Angiography & InterventionsReview
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveSpeckle tracking echocardiography (STE) may be a useful modality for assessing ventricular performance in patients with single ventricle physiology. However, STE's ability to accurately assess ventricular performance in this population is unknown. The objective of this study was to perform a preliminary comparison of STE measures of myocardial deformation to reference standard measures of function derived from pressure-volume loop (PVL) analysis.
designThis was a secondary analysis of a prospective study investigating PVLs in patients with Fontan physiology. PVLs were recorded using microconductance catheters. PVL indices included end-systolic elastance (Ees), arterial elastance (Ea), ventriculo-arterial coupling (Ea/Ees), and the isovolumic relaxation time constant (tau). Patients were included if they had an echocardiogram within 1 month of their catheterization. STE was performed retrospectively using vendor independent software.
resultsSeventeen patients had echocardiograms available for analysis, 12 were right ventricular (RV) dominant. The median age was 8 years (IQR 5-17 years). Circumferential strain (r=-.72, P≤.01) and strain rate (r=-.61, P=.04) correlated with Ea/Ees in those with RV-dominant morphology. Longitudinal strain rate correlated with Ees in those with LV-dominant morphology (r=-.98, P≤.01). Longitudinal EDSR correlated with tau in those with LV-dominant morphology (r=-.90, P=.04).
conclusionsIn this limited sample, circumferential measures of deformation correlated with PVL measures better in patients with RV morphology, while longitudinal measures correlated better with PVL measures in patients with LV morphology. Further validation and investigation into the clinical usefulness of these measures are warranted.
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