Evidence map›Paper›PMID 28752565›Full record

ArticleHuman brain mapping2017

The relationship between subcortical brain volume and striatal dopamine D

Fernando Caravaggio, Jun Ku Chung, Eric Plitman, Isabelle Boileau, Philip Gerretsen, Julia Kim, Yusuke Iwata, Raihaan Patel, M Mallar Chakravarty, Gary Remington and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Human brain mapping, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Fernando CaravaggioResearch Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada.ORCID 0000-0002-9048-4963
Jun Ku ChungResearch Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada.
Eric PlitmanResearch Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada.
Isabelle BoileauResearch Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada.
Philip GerretsenResearch Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada.ORCID 0000-0003-4053-6814
Julia KimResearch Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada.
Yusuke IwataResearch Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada.
Raihaan PatelDepartment of Biological & Biomedical Engineering, McGill University, Montreal, Quebec, H4H 1R3, Canada.
M Mallar ChakravartyDepartment of Biological & Biomedical Engineering, McGill University, Montreal, Quebec, H4H 1R3, Canada.
Gary RemingtonResearch Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada.
Ariel Graff-GuerreroResearch Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada.
Centre for Addiction and Mental Health · CADouglas Mental Health University Institute · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAbnormalities in dopamine (DA) and brain morphology are observed in several neuropsychiatric disorders. However, it is not fully understood how these abnormalities may relate to one another. For such in vivo findings to be used as biomarkers for neuropsychiatric disease, it must be understood how variability in DA relates to brain structure under healthy conditions. We explored how the availability of striatal DA D

methodsData from 62 subjects scanned with [

resultsFor [

conclusionFindings are purely exploratory and presented corrected and uncorrected for multiple comparisons. We hope they will help inform the interpretation of future PET studies where concurrent changes in D

Indexed as

AdultCorpus StriatumFemaleHippocampusHumansMagnetic Resonance ImagingMaleOrgan SizeOxazinesPositron-Emission TomographyRacloprideRadiopharmaceuticalsReceptors, Dopamine D2Receptors, Dopamine D3ThalamusDRD2 protein, humanDRD3 protein, humannaxagolideOxazinesRacloprideRadiopharmaceuticalsReceptors, Dopamine D2Receptors, Dopamine D3D2/3 receptorsdopaminemorphologyPHNOpositron emission tomographyraclopridestriatumvolume

Identifiers

PMID28752565
PMCPMC6867134
OpenAlexW2741112874

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.