Evidence map›Paper›PMID 28752411›Full record

ArticleTranslational stroke research2018

Alcohol Consumption and Aneurysmal Subarachnoid Hemorrhage.

Anil Can, Victor M Castro, Yildirim H Ozdemir, Sarajune Dagen, Dmitriy Dligach, Sean Finan, Sheng Yu, Vivian Gainer, Nancy A Shadick, Guergana Savova and 4 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Translational stroke research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Anil CanDepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Road, Boston, MA, 02115, USA.
Victor M CastroResearch Information Systems and Computing, Partners Healthcare, Boston, MA, USA.
Yildirim H OzdemirDepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Road, Boston, MA, 02115, USA.
Sarajune DagenDepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Road, Boston, MA, 02115, USA.
Dmitriy DligachBoston Children's Hospital Informatics Program, Boston, MA, USA.
Sean FinanBoston Children's Hospital Informatics Program, Boston, MA, USA.
Sheng YuDepartment of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Vivian GainerResearch Information Systems and Computing, Partners Healthcare, Boston, MA, USA.
Nancy A ShadickDivision of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, MA, USA.
Guergana SavovaBoston Children's Hospital Informatics Program, Boston, MA, USA.
Shawn MurphyResearch Information Systems and Computing, Partners Healthcare, Boston, MA, USA.
Tianxi CaiBiostatistics, Harvard School of Public Health, Boston, MA, USA.
Scott T WeissDepartment of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Rose DuDepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Road, Boston, MA, 02115, USA. rdu@bwh.harvard.edu.ORCID 0000-0003-2641-6496
Brigham and Women's Hospital · USBoston Children's Hospital · USMass General Brigham · USHarvard University · USMassachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol consumption may be a modifiable risk factor for rupture of intracranial aneurysms. Our aim is to evaluate the association between ruptured aneurysms and alcohol consumption, intensity, and cessation. The medical records of 4701 patients with 6411 radiographically confirmed intracranial aneurysms diagnosed at the Brigham and Women's Hospital and Massachusetts General Hospital between 1990 and 2016 were reviewed. Individuals were divided into cases with ruptured aneurysms and controls with unruptured aneurysms. Univariable and multivariable logistic regression analyses were performed to determine the association between alcohol consumption and rupture of intracranial aneurysms. In multivariable analysis, current alcohol use (OR 1.36, 95% CI 1.17-1.58) was associated with rupture status compared with never drinkers, whereas former alcohol use was not significant (OR 1.23, 95% CI 0.92-1.63). In addition, the number of alcoholic beverages per day among current alcohol users (OR 1.13, 95% CI 1.04-1.23) was significantly associated with rupture status, whereas alcohol use intensity was not significant among former users (OR 1.02, 95% CI 0.94-1.11). Current alcohol use and intensity are significantly associated with intracranial aneurysm rupture. However, this increased risk does not persist in former alcohol users, emphasizing the potential importance of alcohol cessation in patients harboring unruptured aneurysms.

Indexed as

AdultAgedAlcohol DrinkingFemaleHumansIntracranial AneurysmLogistic ModelsMaleMiddle AgedSubarachnoid HemorrhageAlcoholAneurysmsStrokeSubarachnoid hemorrhage

Identifiers

PMID28752411
OpenAlexW2740593653

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.