Evidence map›Paper›PMID 28752390›Full record

ArticleAngiogenesis2017

PDGFRβ-P2A-CreER

Henar Cuervo, Brianna Pereira, Taliha Nadeem, Mika Lin, Frances Lee, Jan Kitajewski, Chyuan-Sheng Lin

Open access · greenAbstract read
In one paragraph

Article in Angiogenesis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 91 citations in OpenAlex.

  1. Review
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  10. Chemogenetic modulation of CNS pericytes: Impact on pericyte CaMolecular therapy : the journal of the American Society of Gene Therapy · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Henar CuervoDepartment of Physiology and Biophysics, College of Medicine, University of Illinois at Chicago, 835 S. Wolcott Ave. E-202, Chicago, IL, 60612, USA. hcuervo@uic.edu.ORCID http://orcid.org/0000-0001-8293-9377
Brianna PereiraDepartment of Obstetrics/Gynecology, Columbia University Medical Center, New York, NY, USA.
Taliha NadeemDepartment of Physiology and Biophysics, College of Medicine, University of Illinois at Chicago, 835 S. Wolcott Ave. E-202, Chicago, IL, 60612, USA.
Mika LinTransgenic Mouse Shared Resource, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, 1130 St. Nicholas Avenue, ICRC604, New York, NY, 10032, USA.
Frances LeeTransgenic Mouse Shared Resource, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, 1130 St. Nicholas Avenue, ICRC604, New York, NY, 10032, USA.
Jan KitajewskiDepartment of Physiology and Biophysics, College of Medicine, University of Illinois at Chicago, 835 S. Wolcott Ave. E-202, Chicago, IL, 60612, USA.
Chyuan-Sheng LinDepartment of Pathology and Cell Biology, Columbia University Medical Center, 1130 St. Nicholas Avenue, ICRC604, New York, NY, 10032, USA. CSL5@cumc.columbia.edu.
Columbia University Irving Medical Center · USUniversity of Illinois Chicago · USNorthwell Health · USWellesley College · US

Funding

Tumor Biology and Microenvironment ProgramP30CA013696 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Parisa Tehranifar · 1985 to 2026
$115.3M
Notch in Angiogenesis and Vascular BiologyR01HL112626 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Jan K. Kitajewski · 2012 to 2026
$6.3M
NCI NIH HHS P30 CA013696NHLBI NIH HHS R01 HL112626
6 · The paper itself

Abstract

Pericytes are essential mural cells distinguished by their association with small caliber blood vessels and the presence of a basement membrane shared with endothelial cells. Pericyte interaction with the endothelium plays an important role in angiogenesis; however, very few tools are currently available that allow for the targeting of pericytes in mouse models, limiting our ability to understand their biology. We have generated a novel mouse line expressing tamoxifen-inducible Cre-recombinase under the control of the platelet-derived growth factor receptor β promoter: PDGFRβ-P2A-CreER

Indexed as

Genetic TechniquesNeovascularization, PhysiologicAnimalsFemaleGenes, ReporterIntegrasesMaleMice, Inbred C57BLMice, TransgenicPericytesReceptor, Platelet-Derived Growth Factor betaRecombination, GeneticRetinaTamoxifenTime FactorsCre recombinaseIntegrasesReceptor, Platelet-Derived Growth Factor betaTamoxifenMouse modelsMural cellsPericytesPlatelet-derived growth factor β

Identifiers

PMID28752390
PMCPMC5660656
OpenAlexW2741236035

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.