ArticleNeuroradiology2017
Natural history of lesions with the MR imaging appearance of multinodular and vacuolating neuronal tumor.
Article in Neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Multinodular and vacuolating neuronal tumor: magnetic resonance imaging features.Acta neurologica Belgica · 2026Article
- Radiologic characterization and clinical management of multinodular and vacuolating neuronal tumor (MVNT): a retrospective institutional cohort study.Journal of neuro-oncology · 2025Article
- The Mickey Mouse's hand sign in brain MRI points out multinodular and vacuolating neuronal tumors in mesial temporal lobe structures.Journal of neuro-oncology · 2025Article
- Multinodular and Vacuolating Neuronal Tumors: Imaging Features, Diagnosis, and Management Challenges.Diagnostics (Basel, Switzerland) · 2025Review
- Cortically Based Brain Tumors in Children: A Decision-Tree Approach in the Radiology Reading Room.AJNR. American journal of neuroradiology · 2025Review
- Differentiation of multinodular and vacuolating neuronal tumor and dysembryoplastic neuroepithelial tumor based on MRI.Turkish journal of medical sciences · 2025Article
- Multinodular Vacuolating Neuronal Tumors: Symptomatic Presentation Versus Incidental Finding: Case Series and Literature Review.Reports (MDPI) · 2024Article
- Imaging of pediatric glioneuronal and neuronal tumors.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Review
- Multinodular and Vacuolating Neuronal Tumor Initially Misdiagnosed as Acute Cerebral Infarction Presenting With Thunderclap Headache.Journal of clinical neurology (Seoul, Korea) · 2024Article
- Long-Term Follow-up of Multinodular and Vacuolating Neuronal Tumors and Implications for Surveillance Imaging.AJNR. American journal of neuroradiology · 2023Article
- Incidental findings on brain magnetic resonance imaging (MRI) in adults: a review of imaging spectrum, clinical significance, and management.The British journal of radiology · 2023Review
- New Imaging Features of Multinodular and Vacuolating Neuronal Tumor Revealed by Alcohol and Illicit Drugs Consumption.Diagnostics (Basel, Switzerland) · 2022Article
- 2021 WHO classification of tumours of the central nervous system: a review for the neuroradiologist.Neuroradiology · 2022Review
- A multinodular and vacuolating neuronal tumor of the cerebrum (MVNT) with glioma-like appearance.Acta neurologica Belgica · 2021Article
- Multinodular and vacuolating neuronal tumor associated with focal cortical dysplasia in a child with refractory epilepsy: a case report and brief review of literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Review
- Atypical Presentation of Multinodular and Vacuolating Neuronal Tumor of the Cerebrum in a Boy.Journal of neurosciences in rural practice · 2020Article
- Multinodular and Vacuolating Neuronal Tumor of the Cerebrum: Does the Name Require Review?AJNR. American journal of neuroradiology · 2019Article
- Multinodular and Vacuolating Posterior Fossa Lesions of Unknown Significance.AJNR. American journal of neuroradiology · 2019Article
- Multinodular and vacuolating neuronal tumor (MVNT): A presumably incidental and asymptomatic case in an intractable epilepsy patient.Clinical neurophysiology practice · 2019Article
- Multinodular and vacuolating neuronal tumors in epilepsy: dysplasia or neoplasia?Brain pathology (Zurich, Switzerland) · 2018Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMultinodular and vacuolating neuronal tumor (MVNT) have been recently added to the WHO classification of CNS tumors and has not been extensively reported upon in the radiological literature. We report the first radiological and the largest series of cases, aiming to highlight the natural history of lesions with the imaging appearance of MVNT with long follow-up time.
methodsIn this retrospective study, we collected cases with the imaging appearance of MVNT. All lesions were evaluated by using routine MR imaging, with follow-up of up to 93 months. Patient demographics, clinical course, and MRI features of the lesions were recorded.
resultsTwenty-four subjects were enrolled, f/m = 16:8, age range 24-59 years, with a median age of 45 years. The patients' symptoms were often episodic and most frequently due to headaches in 12 (50%), visual symptoms in 6 (25%), seizures in 5 ± 1 (20-25%), paresthesia in 4 (~17%), cognitive difficulties in 4 (~17%), in addition to other variable neurological symptoms, or incidental. A total of 30 lesions identified, 77% of the lesions had gadolinium-enhanced MRI and only 13% showed enhancement. A 6.7% of the lesions that had MRI followed up showed progression, while the rest remained stable up to 93 months interval. All patients had intact neurological examinations (except one case that was diagnosed with optic neuritis), were managed conservatively, and did well.
conclusionThe natural history of lesions with imaging features of MVNT is overall stable from a clinical and imaging appearance over time.
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