ArticleJournal of microbiology (Seoul, Korea)2017
Composition and abundance of microbiota in the pharynx in patients with laryngeal carcinoma and vocal cord polyps.
Article in Journal of microbiology (Seoul, Korea), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Cross-kingdom RNA interference in the dysbiosis-mediated network of vocal fold fibrosis: a pathogenic hypothesis and molecular intervention targets.Frontiers in immunology · 2026Review
- The Role of the Microbiome in Oropharyngeal Squamous Cell Carcinoma: A Systematic Review.Journal of personalized medicine · 2025Review
- Evaluating the prognostic value of microbial communities in predicting recurrence of laryngeal carcinoma: a multicenter case-control study.NPJ biofilms and microbiomes · 2025Article
- Comparison of the bacterial microbiome in the pharynx and nasal cavity of persistent, intermittent carriers and non-carriers ofJournal of medical microbiology · 2024Article
- Cross-comparison of microbiota in the oropharynx, hypopharyngeal squamous cell carcinoma and their adjacent tissues through quantitative microbiome profiling.Journal of oral microbiology · 2022Article
- Oral microbiota in oropharyngeal cancers: Friend or foe?Frontiers in oncology · 2022Article
- Oropharynx microbiota transitions in hypopharyngeal carcinoma treatment of induced chemotherapy followed by surgery.BMC microbiology · 2021Article
- The Role of Bacterial and Fungal Human Respiratory Microbiota in COVID-19 Patients.BioMed research international · 2021Review
- Throat Microbial Community Structure and Functional Changes in Postsurgery Laryngeal Carcinoma Patients.Applied and environmental microbiology · 2020Article
- Selective Bacterial Colonization of the Murine Larynx in a Gnotobiotic Model.Frontiers in microbiology · 2020Article
- Article
- [The Microbiome - The Unscheduled Parameter for Future Therapies].Laryngo- rhino- otologie · 2018Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pharynx is an important site of microbiota colonization, but the bacterial populations at this site have been relatively unexplored by culture-independent approaches. The aim of this study was to characterize the microbiota structure of the pharynx. Pyrosequencing of 16S rRNA gene libraries was used to characterize the pharyngeal microbiota using swab samples from 68 subjects with laryngeal cancer and 28 subjects with vocal cord polyps. Overall, the major phylum was Firmicutes, with Streptococcus as the predominant genus in the pharyngeal communities. Nine core operational taxonomic units detected from Streptococcus, Fusobacterium, Prevotella, Granulicatella, and Veillonella accounted for 21.3% of the total sequences detected. However, there was no difference in bacterial communities in the pharynx from patients with laryngeal cancer and vocal cord polyps. The relative abundance of Firmicutes was inversely correlated with Fusobacteria, Proteobacteria, Actinobacteria, and Bacteroidetes. The correlation was evident at the genus level, and the relative abundance of Streptococcus was inversely associated with Fusobacterium, Leptotrichia, Neisseria, Actinomyces, and Prevotella. This study presented a profile for the overall structure of the microbiota in pharyngeal swab samples. Inverse correlations were found between Streptococcus and other bacterial communities, suggesting that potential antagonism may exist among pharyngeal microbiota.
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