Evidence map›Paper›PMID 28752225›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2017

Grading and outcome prediction of pediatric diffuse astrocytic tumors with diffusion and arterial spin labeling perfusion MRI in comparison with 18F-DOPA PET.

Giovanni Morana, Arnoldo Piccardo, Domenico Tortora, Matteo Puntoni, Mariasavina Severino, Paolo Nozza, Marcello Ravegnani, Alessandro Consales, Samantha Mascelli, Alessandro Raso and 4 more

Registry-linked trialAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05555550 (Evaluation of 18F-Fluciclovine PET-MRI as a Biomarker of Response in Pediatric and Young Adult Patients With Low Grade Gliomas), which is not on this map. Cited by 38 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05555550 early_phase1recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluation of 18F-Fluciclovine PET-MRI as a Biomarker of Response in Pediatric and Young Adult Patients With Low Grade Gliomas (LGG)

TypeinterventionalSponsorChildren's Hospital of PhiladelphiaRan2026 to 2027Enrolled30ConditionsGlioma, Low-grade Glioma, Low Grade Glioma of Brain, Glioma, MalignantArms18F-Fluciclovine
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Pooled it
  4. Arterial Spin-Labeling in Children with Brain Tumor: A Meta-Analysis.AJNR. American journal of neuroradiology · 2018
    Pooled it
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Diagnostic and Dosimetry Features of [Molecular imaging and biology · 2023
    Article
  11. Arterial Spin Labeling for Pediatric Central Nervous System Diseases: Techniques and Clinical Applications.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2023
    Article
  12. Article
  13. Review
  14. Review
  15. Article
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  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Giovanni MoranaNeuroradiology Unit, Istituto Giannina Gaslini, via G. Gaslini 5, 16147, Genoa, Italy. giovannimorana@gaslini.org.ORCID http://orcid.org/0000-0001-8707-5969
Arnoldo PiccardoNuclear Medicine Unit, Ente Ospedaliero Ospedali Galliera, Genoa, Italy.
Domenico TortoraNeuroradiology Unit, Istituto Giannina Gaslini, via G. Gaslini 5, 16147, Genoa, Italy.
Matteo PuntoniClinical Trial Unit, Scientific Directorate, Ente Ospedaliero Ospedali Galliera, Genoa, Italy.
Mariasavina SeverinoNeuroradiology Unit, Istituto Giannina Gaslini, via G. Gaslini 5, 16147, Genoa, Italy.
Paolo NozzaPathology Unit, Istituto Giannina Gaslini, Genoa, Italy.
Marcello RavegnaniNeurosurgery Unit, Istituto Giannina Gaslini, Genoa, Italy.
Alessandro ConsalesNeurosurgery Unit, Istituto Giannina Gaslini, Genoa, Italy.
Samantha MascelliNeurosurgery Unit, Istituto Giannina Gaslini, Genoa, Italy.
Alessandro RasoNeurosurgery Unit, Istituto Giannina Gaslini, Genoa, Italy.
Manlio CabriaNuclear Medicine Unit, Ente Ospedaliero Ospedali Galliera, Genoa, Italy.
Antonio VerricoNeuro-oncology Unit, Istituto Giannina Gaslini, Genoa, Italy.
Claudia MilanaccioNeuro-oncology Unit, Istituto Giannina Gaslini, Genoa, Italy.
Andrea RossiNeuroradiology Unit, Istituto Giannina Gaslini, via G. Gaslini 5, 16147, Genoa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to investigate MRI-derived diffusion weighted imaging (DWI) and arterial spin labeling (ASL) perfusion imaging in comparison with

methodsWe retrospectively analyzed 26 children with histologically proven treatment naïve low and high grade DAT who underwent ASL and DWI performed within 2 weeks of

resultsA significant correlation was demonstrated between rCBF max, rADC min, and

conclusionsDWI, ASL and

Indexed as

Magnetic Resonance ImagingPerfusion ImagingPositron-Emission TomographyAdolescentArteriesBrain NeoplasmsChildChild, PreschoolDiffusionDihydroxyphenylalanineDisease-Free SurvivalFemaleGliomaHumansMaleNeoplasm GradingDihydroxyphenylalaninefluorodopa F 18Spin LabelsArterial spin labelingBrain tumorDiffusion weighted imagingDOPA petGliomaPediatric

Identifiers

PMID28752225

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.