Evidence map›Paper›PMID 28751929›Full record

ArticleOxidative medicine and cellular longevity2017

The Preconditioning of Berberine Suppresses Hydrogen Peroxide-Induced Premature Senescence via Regulation of Sirtuin 1.

Xiaofei Zhu, Haodi Yue, Xiaofang Guo, Jingyi Yang, Jingshuo Liu, Jiangtao Liu, Ruijie Wang, Wenjuan Zhu

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
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  5. Article
  6. Article
  7. Nutrition Interventions of Herbal Compounds on Cellular Senescence.Oxidative medicine and cellular longevity · 2022
    Review
  8. Article
  9. Review
  10. Review
  11. Article
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  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xiaofei ZhuDepartment of Clinical Immunology, Research Center for Immunology, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang 453003, China.ORCID 0000-0001-6360-140X
Haodi YueDepartment of Clinical Immunology, Research Center for Immunology, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang 453003, China.
Xiaofang GuoDepartment of Microbiology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang 453003, China.
Jingyi YangDepartment of Clinical Immunology, Research Center for Immunology, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang 453003, China.
Jingshuo LiuDepartment of Clinical Immunology, Research Center for Immunology, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang 453003, China.
Jiangtao LiuDepartment of Clinical Immunology, Research Center for Immunology, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang 453003, China.
Ruijie WangDepartment of Clinical Immunology, Research Center for Immunology, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang 453003, China.
Wenjuan ZhuDepartment of Clinical Immunology, Research Center for Immunology, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang 453003, China.
Xinxiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With a long history of application in Chinese traditional medicine, berberine (BBR) was reported to exhibit healthspan-extending properties in some age-related diseases, such as type 2 diabetes and atherosclerosis. However, the antiaging mechanism of BBR is not completely clear. By means of hydrogen peroxide- (H

Indexed as

BerberineCell LineCellular SenescenceCheckpoint Kinase 2FibroblastsHumansHydrogen PeroxideOxidative StressSirtuin 1BerberineCheckpoint Kinase 2CHEK2 protein, humanHydrogen PeroxideSIRT1 protein, humanSirtuin 1

Identifiers

PMID28751929
PMCPMC5511663
OpenAlexW2729458111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.