Evidence map›Paper›PMID 28751888›Full record

ArticleFrontiers in microbiology2017

Identification of the Components Involved in Cyclic Di-AMP Signaling in

Cedric Blötz, Katrin Treffon, Volkhard Kaever, Frank Schwede, Elke Hammer, Jörg Stülke

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 56 citations in OpenAlex.

  1. Mislocalization of PBPs inMicrobiology spectrum · 2026
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  2. Review
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  4. Review
  5. Regulation of potassium homeostasis inFrontiers in microbiology · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Bacterial cell volume regulation and the importance of cyclic di-AMP.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Nano-RNases: oligo- or dinucleases?FEMS microbiology reviews · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Cedric BlötzDepartment of General Microbiology, Institute of Microbiology and Genetics, Georg-August University GöttingenGöttingen, Germany.
Katrin TreffonDepartment of General Microbiology, Institute of Microbiology and Genetics, Georg-August University GöttingenGöttingen, Germany.
Volkhard KaeverResearch Core Unit Metabolomics, Hannover Medical SchoolHannover, Germany.
Frank SchwedeBiolog Life Science InstituteBremen, Germany.
Elke HammerDepartment of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine GreifswaldGreifswald, Germany.
Jörg StülkeDepartment of General Microbiology, Institute of Microbiology and Genetics, Georg-August University GöttingenGöttingen, Germany.
University of Göttingen · DEBiolog Life Science Institute · DEMedizinische Hochschule Hannover · DEUniversitätsmedizin Greifswald · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria often use cyclic dinucleotides as second messengers for signal transduction. While the classical molecule c-di-GMP is involved in lifestyle selection, the functions of the more recently discovered signaling nucleotide cyclic di-AMP are less defined. For many Gram-positive bacteria, c-di-AMP is essential for growth suggesting its involvement in a key cellular function. We have analyzed c-di-AMP signaling in the genome-reduced pathogenic bacterium

Indexed as

c-di-AMPdiadenylate cyclaseMollicutesphosphodiesterasepotassium uptakesecond messenger

Identifiers

PMID28751888
PMCPMC5508000
OpenAlexW2724879968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.