Evidence map›Paper›PMID 28751853›Full record

ArticleAdvanced functional materials2016

Tracking and Quantification of Magnetically Labeled Stem Cells using Magnetic Resonance Imaging.

Forrest Goodfellow, Gregory A Simchick, Luke J Mortensen, Steven L Stice, Qun Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced functional materials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Imaging the fate of CAR-T cellsFrontiers in immunology · 2026
    Review
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  14. An EfficientContrast media & molecular imaging · 2019
    Article
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Forrest GoodfellowRegenerative Bioscience Center.
Gregory A SimchickBioimaging Research Center, Regenerative Bioscience Center, and Department of Physics University of Georgia, Athens, GA. 30602, USA.
Luke J MortensenRegenerative Bioscience Center and College of Engineering.
Steven L SticeRegenerative Bioscience Center.
Qun ZhaoBioimaging Research Center, Regenerative Bioscience Center, and Department of Physics University of Georgia, Athens, GA. 30602, USA.

Funding

MRS/MRI for Small Animal Models of DiseaseS10RR023706 · NCRR · UNIVERSITY OF GEORGIA · PI PRESTEGARD, JAMES H. · 2009 to 2009
$500k
NCRR NIH HHS S10 RR023706
6 · The paper itself

Abstract

Stem cell based therapies have critical impacts on treatments and cures of diseases such as neurodegenerative or cardiovascular disease. In vivo tracking of stem cells labeled with magnetic contrast agents is of particular interest and importance as it allows for monitoring of the cells' bio-distribution, viability, and physiological responses. Herein, recent advances are introduced in tracking and quantification of super-paramagnetic iron oxide (SPIO) nanoparticles-labeled cells with magnetic resonance imaging, a noninvasive approach that can longitudinally monitor transplanted cells. This is followed by recent translational research on human stem cells that are dual-labeled with green fluorescence protein (GFP) and SPIO nanoparticles, then transplanted and tracked in a chicken embryo model. Cell labeling efficiency, viability, and cell differentiation are also presented.

Indexed as

chick embryoMRISPIOstem celltracking

Identifiers

PMID28751853
PMCPMC5526633

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.