Evidence map›Paper›PMID 28751776›Full record

ArticleScientific reports2017

Hobit expression by a subset of human liver-resident CD56

Sebastian Lunemann, Gloria Martrus, Hanna Goebels, Tobias Kautz, Annika Langeneckert, Wilhelm Salzberger, Martina Koch, Madeleine J Bunders, Björn Nashan, Klaas P J M van Gisbergen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. Origin of Hypofunctional CD103European journal of immunology · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Intestinal CD8European journal of immunology · 2022
    Review
  8. Article
  9. Review
  10. Article
  11. Tissue-Resident Immune Cells in Humans.Annual review of immunology · 2022
    Review
  12. Article
  13. Review
  14. Article
  15. Human NK cells, their receptors and function.European journal of immunology · 2021
    Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Discipline in Stages: Regulating CD8Frontiers in immunology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Sebastian LunemannDepartment of Virus Immunology, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Gloria MartrusDepartment of Virus Immunology, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Hanna GoebelsDepartment of Virus Immunology, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Tobias KautzDepartment of Virus Immunology, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Annika LangeneckertDepartment of Virus Immunology, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Wilhelm SalzbergerDepartment of Virus Immunology, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Martina KochDepartment of Hepatobiliary Surgery and Transplantation, University Medical Center Hamburg, Hamburg, Germany.
Madeleine J BundersDepartment of Virus Immunology, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Björn NashanDepartment of Hepatobiliary Surgery and Transplantation, University Medical Center Hamburg, Hamburg, Germany.
Klaas P J M van GisbergenDepartment of Experimental Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.
Marcus AltfeldDepartment of Virus Immunology, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany. marcus.altfeld@hpi.uni-hamburg.de.
Leibniz Institute of Virology (LIV) · DEAcademic Medical Center · NLUniversität Hamburg · DEUniversity Medical Center Hamburg-Eppendorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune responses show a high degree of tissue specificity shaped by factors influencing tissue egress and retention of immune cells. The transcription factor Hobit was recently shown to regulate tissue-residency in mice. Whether Hobit acts in a similar capacity in humans remains unknown. Our aim was to assess the expression and contribution of Hobit to tissue-residency of Natural Killer (NK) cells in the human liver. The human liver was enriched for CD56

Indexed as

Gene Expression RegulationCD56 AntigenHumansKiller Cells, NaturalLiverReceptors, ChemokineTranscription FactorsCD56 AntigenReceptors, ChemokineTranscription FactorsZNF683 protein, human

Identifiers

PMID28751776
PMCPMC5532267
OpenAlexW2738389197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.