Evidence map›Paper›PMID 28751774›Full record

ArticleLeukemia2017

The assembly competence domain is essential for inv(16)-associated acute myeloid leukemia.

H-G Kim, J LeGrand, C S Swindle, H J Nick, R A Oster, D Chen, S Purohit-Ghelani, C V Cotta, R Ko, L Gartland and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

H-G KimDepartment of Microbiology, University of Alabama-Birmingham, Birmingham, AL, USA.
J LeGrandDepartment of Microbiology, University of Alabama-Birmingham, Birmingham, AL, USA.
C S SwindleDepartment of Microbiology, University of Alabama-Birmingham, Birmingham, AL, USA.
H J NickDepartment of Microbiology, University of Alabama-Birmingham, Birmingham, AL, USA.
R A OsterDepartment of Medicine, University of Alabama-Birmingham, Birmingham, AL, USA.
D ChenDepartment of Medicine, University of Alabama-Birmingham, Birmingham, AL, USA.
S Purohit-GhelaniDepartment of Microbiology, University of Alabama-Birmingham, Birmingham, AL, USA.
C V CottaDepartment of Pathology, University of Alabama-Birmingham, Birmingham, AL, USA.
R KoDepartment of Biochemistry and Molecular Genetics, University of Alabama-Birmingham, Birmingham, AL, USA.
L GartlandDepartment of Microbiology, University of Alabama-Birmingham, Birmingham, AL, USA.
V ReddyDepartment of Pathology, University of Alabama-Birmingham, Birmingham, AL, USA.
S W HiebertDepartment of Biochemistry, Ingram Cancer Center, Vanderbilt University, Nashville, TN, USA.
A D FriedmanDivision of Pediatric Oncology, Johns Hopkins University, Baltimore, MD, USA.
C A KlugDepartment of Microbiology, University of Alabama-Birmingham, Birmingham, AL, USA.

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
Role of AML1-ETO in Acute LeukemiaR01CA064140 · NCI · VANDERBILT UNIVERSITY · PI HIEBERT, SCOTT W · 1994 to 2018
$5.7M
MECHANISM OF INV(16) MEDIATED LEUKEMOGENESISR01CA087549 · NCI · VANDERBILT UNIVERSITY · PI HIEBERT, SCOTT W · 2000 to 2009
$3.8M
Regulation of Monocyte and Granulocyte Lineage SpecificationR01HL089176 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI FRIEDMAN, ALAN D · 2009 to 2013
$2.0M
Regulation of transcription and tumor suppression by MTG family membersR01CA178030 · NCI · VANDERBILT UNIVERSITY · PI HIEBERT, SCOTT W · 2014 to 2018
$1.8M
Role of NF-kB in hematopoietic stem cells and leukemia-initiating cell formationR01CA144248 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KLUG, CHRISTOPHER · 2010 to 2014
$1.5M
Analysis of a murine model of the AML1-ETO translocationR01CA096798 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KLUG, CHRISTOPHER · 2004 to 2009
$1.5M
NCI NIH HHS P30 CA013148NCI NIH HHS R01 CA064140NCI NIH HHS R01 CA087549NCI NIH HHS R01 CA096798NCI NIH HHS R01 CA144248NCI NIH HHS R01 CA178030NHLBI NIH HHS R01 HL089176
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell Line, TumorChromosome InversionChromosomes, Human, Pair 16Core Binding Factor Alpha 2 SubunitCore Binding FactorsDNA-Binding ProteinsHumansLeukemia, Myeloid, AcuteMaleMiceMice, Inbred C57BLTranscription FactorsCore Binding Factor Alpha 2 SubunitCore Binding FactorsDNA-Binding ProteinsTranscription Factors

Identifiers

PMID28751774
PMCPMC5628135

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.