Evidence map›Paper›PMID 28751772›Full record

ArticleLeukemia2017

Inhibition of reactive oxygen species limits expansion of chronic lymphocytic leukemia cells.

B Yigit, N Wang, S-S Chen, N Chiorazzi, C Terhorst

Abstract read
PubMed Publisher
In one paragraph

Article in Leukemia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Cell toxicity mechanism and biomarker.Clinical and translational medicine · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

B YigitDivision of Immunology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
N WangDivision of Immunology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
S-S ChenKarches Center for Chronic Lymphocytic Leukemia Research, The Feinstein Institute for Medical Research, Manhasset, NY, USA.
N ChiorazziKarches Center for Chronic Lymphocytic Leukemia Research, The Feinstein Institute for Medical Research, Manhasset, NY, USA.
C TerhorstDivision of Immunology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Funding

The Slamf3, Slamf5, and Slamf6 receptor-induced pathways to murine lupusP01AI065687 · NIAID · BETH ISRAEL DEACONESS MEDICAL CENTER · PI TERHORST, CORNELIS P · 2006 to 2016
$14.7M
NIAID NIH HHS P01 AI065687
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsB-LymphocytesCell Line, TumorHumansImmunoglobulin MLeukemia, Lymphocytic, Chronic, B-CellMiceProtein Tyrosine PhosphatasesReactive Oxygen SpeciesImmunoglobulin MProtein Tyrosine PhosphatasesReactive Oxygen Species

Identifiers

PMID28751772

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.