Evidence map›Paper›PMID 28751769›Full record

Trial reportLeukemia2017

Phase I/II study of the deacetylase inhibitor panobinostat after allogeneic stem cell transplantation in patients with high-risk MDS or AML (PANOBEST trial).

G Bug, A Burchert, E-M Wagner, N Kröger, T Berg, S Güller, S K Metzelder, A Wolf, S Hünecke, P Bader and 3 more

Abstract readClinical Trial, Phase IClinical Trial, Phase IIMulticenter Study
In one paragraph

Trial report in Leukemia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

G BugDepartment of Medicine II, University Hospital, Frankfurt, Germany.
A BurchertDepartment of Hematology, Oncology and Immunology, Universitätsklinikum, Marburg, Germany.
E-M WagnerThird Department of Medicine, University Medical Center, Mainz, Germany.
N KrögerDepartment of Stem Cell Transplantation, University Hospital, Hamburg, Germany.
T BergDepartment of Medicine II, University Hospital, Frankfurt, Germany.
S GüllerDepartment of Medicine II, University Hospital, Frankfurt, Germany.
S K MetzelderDepartment of Hematology, Oncology and Immunology, Universitätsklinikum, Marburg, Germany.
A WolfDepartment of Medicine II, University Hospital, Frankfurt, Germany.
S HüneckeDepartment for Children and Adolescents, University Hospital, Frankfurt, Germany.
P BaderDepartment for Children and Adolescents, University Hospital, Frankfurt, Germany.
J ScheteligMedizinische Klinik und Poliklinik I, Universitätsklinikum, Dresden, Germany.
H ServeDepartment of Medicine II, University Hospital, Frankfurt, Germany.
O G OttmannDivision of Cancer and Genetics, Department of Haematology, Cardiff University, Cardiff, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAntineoplastic AgentsFemaleHematopoietic Stem Cell TransplantationHistone Deacetylase InhibitorsHumansHydroxamic AcidsIndolesLeukemia, Myeloid, AcuteMaleMiddle AgedMyelodysplastic SyndromesPanobinostatYoung AdultAntineoplastic AgentsHistone Deacetylase InhibitorsHydroxamic AcidsIndolesPanobinostat

Identifiers

PMID28751769
PMCPMC5668491

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.