ArticleScientific reports2017
Gastric and intestinal proteases resistance of chicken acidic chitinase nominates chitin-containing organisms for alternative whole edible diets for poultry.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Influence of the administration route and dose on the expression and antibody responses of a reporter and avian influenza self-amplifying mRNA vaccine in poultry.The veterinary quarterly · 2026Article
- Key Amino Acids Controlling pH Optima in Avian Chia Paralogs: Mechanistic Insights into Functional Divergence.Molecules (Basel, Switzerland) · 2026Article
- Amplicon sequence data from the gut microbiota of broiler chickens fed black soldier fly (Microbiology resource announcements · 2026Article
- Accessing the impact of harvest weights of Tenebrio molitor on amino acid digestibility and metabolizable energy in cecectomized laying hens.Journal of the science of food and agriculture · 2026Article
- Review
- Growth performance, meat quality, cecal microbiota and metabolomics profile of turkeys fed diets containing black soldier fly (Hermetia illucens) meal.Scientific reports · 2025Article
- Hyperactivation of human acidic chitinase (Chia) for potential medical use.The Journal of biological chemistry · 2025Article
- Low-FatInsects · 2024Article
- Characterization ofFood science & nutrition · 2024Article
- The gastric mucosa of Atlantic salmon (Salmo salar) is abundant in highly active chitinases.FEBS open bio · 2024Article
- A Systematic Review and Metanalysis on the Use ofVeterinary sciences · 2023Review
- Evolutionary activation of acidic chitinase in herbivores through the H128R mutation in ruminant livestock.iScience · 2023Article
- Gene family expansion and functional diversification of chitinase and chitin synthase genes in Atlantic salmon (Salmo salar).G3 (Bethesda, Md.) · 2023Article
- Effects of Black Soldier Fly Larvae (Veterinary sciences · 2023Article
- Chitinase-Assisted Bioconversion of Chitinous Waste for Development of Value-Added Chito-Oligosaccharides Products.Biology · 2023Review
- Article
- Effect of insect protein and protease on growth performance, blood profiles, fecal microflora and gas emission in growing pig.Journal of animal science and technology · 2022Article
- Nutritional Composition of Black Soldier Fly Larvae (Insects · 2022Review
- Crab-Eating Monkey Acidic Chitinase (CHIA) Efficiently Degrades Chitin and Chitosan under Acidic and High-Temperature Conditions.Molecules (Basel, Switzerland) · 2022Article
- Noninsect-Based Diet Leads to Structural and Functional Changes of Acidic Chitinase in Carnivora.Molecular biology and evolution · 2022Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chitin, a polymer of N-acetyl-D-glucosamine (GlcNAc), functions as a major structural component in crustaceans, insects and fungi and is the second most abundant polysaccharide in the nature. Although these chitin-containing organisms have been suggested as novel animal feed resources, chitin has long been considered as indigestible fibers in the animal body. Recently, we reported that acidic chitinase (Chia) is a protease-resistant major glycosidase in mouse gastrointestinal tract (GIT) and that it digests chitin in the mouse stomach. However, the physiological role of Chia in other animals including poultry remains unknown. Here, we report that Chia can function as a digestive enzyme that breaks down chitin-containing organisms in chicken GIT. Chia mRNA is predominantly expressed in the glandular stomach tissue in normal chicken. We also show that chicken Chia has a robust chitinolytic activity at pH 2.0 and is highly resistant to proteolysis by pepsin and trypsin/chymotrypsin under conditions mimicking GIT. Chia degraded shells of mealworm larvae in the presence of digestive proteases and produced (GlcNAc)
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