Evidence map›Paper›PMID 28751756›Full record

ArticleBritish journal of cancer2017

Knowledge or noise? Making sense of General Practitioners' and Consultant use of 2-week-wait referrals for suspected cancer.

Conan Donnelly, Nigel Hart, Alan David McCrorie, Lesley Anderson, Michael Donnelly, Peter Murchie, Anna Gavin

Open access · hybridAbstract read
In one paragraph

Article in British journal of cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Direct access cancer testing in primary care: a systematic review of use and clinical outcomes.The British journal of general practice : the journal of the Royal College of General Practitioners · 2018
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Conan DonnellyN. Ireland Cancer Registry, Queen's University Belfast, Mulhouse Building, Grosvenor Road, Belfast BT12 6DP, Northern Ireland.
Nigel HartDepartment of General Practice and Primary Care, Queen's University Belfast, Dunluce Health Centre, 1 Dunluce Avenue, Belfast BT9 7HR, Northern Ireland.
Alan David McCrorieQueen's University Belfast School of Medicine, Dentistry &Biomedical Sciences, Whitla Medical Building, 97 Lisburn Road, Belfast BT9 7BL, Northern Ireland.
Lesley AndersonCentre for Public Health, Queen's University Belfast, Institute of Clinical Sciences Building, Grosvenor Road, Belfast BT12 6DP, Northern Ireland.
Michael DonnellyCentre for Public Health, Queen's University Belfast, Institute of Clinical Sciences Building, Grosvenor Road, Belfast BT12 6DP, Northern Ireland.
Peter MurchieThe Institute of Applied Health Sciences, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen AB25 2ZD, Scotland.
Anna GavinN. Ireland Cancer Registry, Queen's University Belfast, Mulhouse Building, Grosvenor Road, Belfast BT12 6DP, Northern Ireland.
Queen's University Belfast · GBUniversity of Aberdeen · GB

Funding

Cancer Research UK 14000Medical Research Council MR/K023241/1
6 · The paper itself

Abstract

backgroundEarly diagnosis and treatment of cancer is the goal of the 2-week-wait referral pathway (2WW). Variation exists between General Practice use of 2WW and rates of consultant reprioritisation of GP referral from routine to 2WW (Consultant Upgrade). We investigated variation in General Practice and Consultant Upgrade 2WW referral activity.

methodsData from 185 000 referrals and 29 000 cancers recorded between 2011 and 2013 from the Northern Ireland Cancer Waiting Time database (CaPPS) were analysed to ascertain standardised referral rate ratios, detection rate (DR) (=sensitivity) and conversion rate (CR) (=positive predictive value) for Practice 2WW referrals and Consultant Upgrade 2WW. Metrics were compared using Spearman's rank correlation co-efficients.

resultsThere was consistency in Practice and Consultant Upgrade 2WW referral rates over time, though not for annual DR (Spearman's ρ<0.37) or CR (Spearman's ρ<0.26). Practice 2WW referral rates correlated negatively with CR and positively with DR while correlations between DR and CR were restricted to single-year comparisons in Practice 2WW. In Consultant Upgrade, 2WW CR and DR were strongly correlated but only when the same cancers were included in both rates.

conclusionsResults suggest 'random case mix' explains previously reported associations between CR and DR with more 'hard to detect' cancers in some Practices than in others in a given year corresponding to lower DR and CR. Use of Practice and Consultant Upgrade 2WW referral metrics to gauge General Practice performance may be misleading.

Indexed as

Early Detection of CancerTime FactorsDiagnosis-Related GroupsFemaleGeneral PracticeHumansMaleNeoplasmsNorthern IrelandPredictive Value of TestsQuality Indicators, Health CareReferral and Consultation

Identifiers

PMID28751756
PMCPMC5572170
OpenAlexW2739668420

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.