Evidence map›Paper›PMID 28751688›Full record

ArticleScientific reports2017

Enhanced efficiency of cell death by lysosome-specific photodamage.

Tayana Mazin Tsubone, Waleska Kerllen Martins, Christiane Pavani, Helena Couto Junqueira, Rosangela Itri, Maurício S Baptista

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 128 citations in OpenAlex.

  1. Guideline
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  13. Phenazine Cations as Anticancer TheranosticsJournal of the American Chemical Society · 2024
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  17. Phosphorescent Metal Halide Nanoclusters for Tunable Photodynamic Therapy.Chemistry (Weinheim an der Bergstrasse, Germany) · 2023
    Article
  18. Exploring the sonodynamic effects of bacteriochlorophyll a.Frontiers in bioengineering and biotechnology · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tayana Mazin TsuboneInstituto de Química, Universidade de São Paulo, São Paulo-SP, Brazil.ORCID 0000-0003-4795-4568
Waleska Kerllen MartinsInstituto de Química, Universidade de São Paulo, São Paulo-SP, Brazil.
Christiane PavaniInstituto de Química, Universidade de São Paulo, São Paulo-SP, Brazil.
Helena Couto JunqueiraInstituto de Química, Universidade de São Paulo, São Paulo-SP, Brazil.
Rosangela ItriInstituto de Física, Universidade de São Paulo, São Paulo-SP, Brazil.
Maurício S BaptistaInstituto de Química, Universidade de São Paulo, São Paulo-SP, Brazil. baptista@iq.usp.br.ORCID 0000-0001-7079-7666
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mobilization of specific mechanisms of regulated cell death is a promising alternative to treat challenging illness such as neurodegenerative disease and cancer. The use of light to activate these mechanisms may provide a route for target-specific therapies. Two asymmetric porphyrins with opposite charges, the negatively charged TPPS

Indexed as

ApoptosisBenzenesulfonatesCell MembraneCell SurvivalHeLa CellsHumansKineticsLightLysosomesMembranes, ArtificialMitochondriaPhotochemotherapyPhotosensitizing AgentsPorphyrinsPyridinium CompoundsStatic Electricity5,15-bis(4-N-methylpyridyl)-10,20-diphenylporphyrinBenzenesulfonatesMembranes, ArtificialPhotosensitizing AgentsPorphyrinsPyridinium CompoundsTPPS2a chlorin

Identifiers

PMID28751688
PMCPMC5532215
OpenAlexW2736785434

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.