ArticleScientific reports2017
Comparison of micro-CT imaging and histology for approximal caries detection.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Validity of micro-CT forDento maxillo facial radiology · 2020Pooled it
- Deep learning-driven super-resolution for cone-beam computed tomography: AnImaging science in dentistry · 2026Article
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- Accuracy of deep learning-based AI models for early caries lesion detection: the influence of annotation quality and reference choice.Clinical oral investigations · 2025Article
- Enhancement of early proximal caries annotations in radiographs: introducing the Diagnostic Insights for Radiographic Early-caries with micro-CT (ACTA-DIRECT) dataset.BMC oral health · 2024Article
- Assessment of the Effect on Periodontitis of Antibiotic Therapy and Bacterial Lysate Treatment.International journal of molecular sciences · 2024Article
- Proximal Caries Detection Using Short-Wave Infrared Transillumination at Wavelengths of 1050, 1200 and 1300 nm in Permanent Posterior Human Teeth.Diagnostics (Basel, Switzerland) · 2023Article
- Clinical Performance of Diagnostic Methods in Third Molar Teeth with Early Occlusal Caries.Diagnostics (Basel, Switzerland) · 2023Article
- Analysis of the transparent surface layer formed at the surfaces of arrested enamel caries lesions with tomographic imaging methods.JADA foundational science · 2023Article
- The effect of spatial resolution on deep learning classification of lung cancer histopathology.BJR open · 2023Article
- New Caries Diagnostic Tools in Intraoral Scanners: A Comparative In Vitro Study to Established Methods in Permanent and Primary Teeth.Sensors (Basel, Switzerland) · 2022Article
- Micro-computed tomography in preventive and restorative dental research: A review.Imaging science in dentistry · 2021Review
- Micro-computed tomography utility for estimation of intraparenchymal spinal cord cystic lesions in small animals.Neural regeneration research · 2021Article
- Near-infrared reflection at 780 nm for detection of early proximal caries in posterior permanent teeth in vitro.Dento maxillo facial radiology · 2021Article
- In vitro comparison of two types of digital X-ray sensors for proximal caries detection validated by micro-computed tomography.Dento maxillo facial radiology · 2021Article
- Diagnostic validity of the use of ICDAS II and DIAGNOdent pen verified by micro-computed tomography for the detection of occlusal caries lesions-an in vitro evaluation.Lasers in medical science · 2019Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Histological sectioning is a generally accepted in vitro validation method for caries detection techniques. However, it requires cumbersome sample preparation and induces irreversible sample destruction. Micro-Computer Tomography (micro-CT) allows non-destructive imaging of tooth structure. The aim of this study was to compare the performance of histological sectioning and micro-CT imaging in detecting approximal carious lesions. Unlike previous studies, evaluation is objectified by comparing visual appearance of exactly corresponding anatomical regions. Sixty extracted human teeth were scanned with a desktop micro CT system. Axial histological slices were prepared and photographed. Sample preparation, combined with dedicated image processing, ensured selection of identical anatomical regions on radiographic and histological images. Evaluation of the presence and extent of carious lesions was performed by four dentists using custom-designed software. Each section was scored independently (histo or micro CT). Scores of approximal surfaces were retained for further analysis. Spearman's correlation coefficients (0.738 to 0.829, p < 0.0001) showed a good agreement between signs of carious lesions in the identical region obtained with both methods. Bland-Altman plots showed that 90.76% of the data points were within the limits of agreement. Micro-CT imaging was shown to provide an interesting alternative to histological sectioning as detection method for carious lesions.
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