Evidence map›Paper›PMID 28751642›Full record

ArticleScientific reports2017

Anti-obesity and anti-inflammatory effects of synthetic acetic acid vinegar and Nipa vinegar on high-fat-diet-induced obese mice.

Boon Kee Beh, Nurul Elyani Mohamad, Swee Keong Yeap, Huynh Ky, Sook Yee Boo, Joelle Yi Heng Chua, Sheau Wei Tan, Wan Yong Ho, Shaiful Adzni Sharifuddin, Kamariah Long and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Article
  2. Review
  3. Regulation mechanism ofFrontiers in nutrition · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Optimization of Liquid Fermentation ofMolecules (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Fruit vinegar as a promising source of natural anti-inflammatory agents: an up-to-date review.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024
    Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Effect and Correlation ofFoods (Basel, Switzerland) · 2022
    Article
  15. Food science and biotechnology · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Boon Kee BehBiotechnology Research Centre, Malaysian Agricultural Research and Development Institute (MARDI), Serdang, Selangor, 43400, Malaysia.
Nurul Elyani MohamadDepartment of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Science, Universiti Putra Malaysia, Serdang, Selangor, 43400, Malaysia.
Swee Keong YeapInstitute of Bioscience, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
Huynh KyDepartment of Agriculture Genetics and Breeding, College of Agriculture and Applied Biology, Cantho University, Can Tho, 84071, Vietnam.
Sook Yee BooBioEasy Sdn Bhd, Setia Alam, Shah Alam, Selangor, Malaysia.
Joelle Yi Heng ChuaBioEasy Sdn Bhd, Setia Alam, Shah Alam, Selangor, Malaysia.
Sheau Wei TanInstitute of Bioscience, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
Wan Yong HoSchool of Biomedical Sciences, The University of Nottingham Malaysia Campus, Jalan Broga, 43500, Semenyih, Selangor, Malaysia.
Shaiful Adzni SharifuddinBiotechnology Research Centre, Malaysian Agricultural Research and Development Institute (MARDI), Serdang, Selangor, 43400, Malaysia.
Kamariah LongBiotechnology Research Centre, Malaysian Agricultural Research and Development Institute (MARDI), Serdang, Selangor, 43400, Malaysia.
Noorjahan Banu AlitheenInstitute of Bioscience, Universiti Putra Malaysia, Serdang, Selangor, Malaysia. noorjahan@upm.edu.my.ORCID 0000-0003-1966-8580

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, food-based bioactive ingredients, such as vinegar, have been proposed as a potential solution to overcome the global obesity epidemic. Although acetic acid has been identified as the main component in vinegar that contributes to its anti-obesity effect, reports have shown that vinegar produced from different starting materials possess different degrees of bioactivity. This study was performed to compare the anti-obesity and anti-inflammatory effects of synthetic acetic acid vinegar and Nipa vinegar in mice fed a high-fat diet. In this work, mice were fed a high-fat diet for 33 weeks. At the start of week 24, obese mice were orally fed synthetic acetic acid vinegar or Nipa vinegar (0.08 and 2 ml/kg BW) until the end of week 33. Mice fed a standard pellet diet served as a control. Although both synthetic acetic acid vinegar and Nipa vinegar effectively reduced food intake and body weight, a high dose of Nipa vinegar more effectively reduced lipid deposition, improved the serum lipid profile, increased adipokine expression and suppressed inflammation in the obese mice. Thus, a high dose of Nipa vinegar may potentially alleviate obesity by altering the lipid metabolism, inflammation and gut microbe composition in high-fat-diet-induced obese mice.

Indexed as

Acetic AcidAdipokinesAnimalsAnti-Inflammatory AgentsAnti-Obesity AgentsCholesterolDiet, High-FatGene Expression RegulationLipid MetabolismLipoproteins, HDLLipoproteins, LDLMice, Inbred C57BLMice, ObeseObesityTriglyceridesAcetic AcidAdipokinesAnti-Inflammatory AgentsAnti-Obesity AgentsCholesterolLipoproteins, HDLLipoproteins, LDLTriglycerides

Identifiers

PMID28751642
PMCPMC5532206

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.