Evidence map›Paper›PMID 28751604›Full record

ArticleScience (New York, N.Y.)2017

Tough adhesives for diverse wet surfaces.

J Li, A D Celiz, J Yang, Q Yang, I Wamala, W Whyte, B R Seo, N V Vasilyev, J J Vlassak, Z Suo and 1 more

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 372 papers.

0numbers the graph read from it
0cells of the map it votes in
372citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

372 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
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  9. Data-Driven Design of Self-Adhesive Epidermal Electrodes and Sensors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Tissue-bioelectronics interfaces.Chemical Society reviews · 2026
    Review
  19. Review
  20. Review

312 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

J LiJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0002-1128-6804
A D CelizWyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0003-4568-7734
J YangJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0003-2446-0004
Q YangJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0001-8029-1327
I WamalaDepartments of Cardiac Surgery, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0001-8030-9283
W WhyteJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0002-2458-4149
B R SeoJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.
N V VasilyevDepartments of Cardiac Surgery, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0002-8181-8044
J J VlassakJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.
Z SuoJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.
D J MooneyJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA. mooneyd@seas.harvard.edu.ORCID 0000-0001-6299-1194

Funding

POLYMERIC MATRICES WITH DEFINED CELL ADHESION AND MECHANR01DE013033 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOONEY, DAVID J · 1998 to 2018
$3.0M
NIDCR NIH HHS R01 DE013033
6 · The paper itself

Abstract

Adhesion to wet and dynamic surfaces, including biological tissues, is important in many fields but has proven to be extremely challenging. Existing adhesives are cytotoxic, adhere weakly to tissues, or cannot be used in wet environments. We report a bioinspired design for adhesives consisting of two layers: an adhesive surface and a dissipative matrix. The former adheres to the substrate by electrostatic interactions, covalent bonds, and physical interpenetration. The latter amplifies energy dissipation through hysteresis. The two layers synergistically lead to higher adhesion energies on wet surfaces as compared with those of existing adhesives. Adhesion occurs within minutes, independent of blood exposure and compatible with in vivo dynamic movements. This family of adhesives may be useful in many areas of application, including tissue adhesives, wound dressings, and tissue repair.

Indexed as

AnimalsBiocompatible MaterialsRatsStatic ElectricitySwineTissue AdhesivesBiocompatible MaterialsTissue Adhesives

Identifiers

PMID28751604
PMCPMC5905340

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.