Evidence map›Paper›PMID 28751561›Full record

ArticleHaematologica2017

Exome sequencing identifies recurrent

Laurent Jallades, Lucile Baseggio, Pierre Sujobert, Sarah Huet, Kaddour Chabane, Evelyne Callet-Bauchu, Aurélie Verney, Sandrine Hayette, Jean-Pierre Desvignes, David Salgado and 8 more

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 4 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Pooled it
  5. Cancers · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Genetic alterations in mature B- and T-cell lymphomas - a practical guide to WHO-HAEM5.Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V · 2024
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Role of RNA Splicing Mutations in Diffuse Large B Cell Lymphoma.International journal of general medicine · 2023
    Review
  16. Mcm2 hypomorph leads to acute leukemia or hematopoietic stem cell failure, dependent on genetic context.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 1 country.

Laurent JalladesHospices Civils de Lyon, Centre Hospitalier Lyon Sud, Laboratoire d'Hématologie, Pierre-Bénite, France.
Lucile BaseggioHospices Civils de Lyon, Centre Hospitalier Lyon Sud, Laboratoire d'Hématologie, Pierre-Bénite, France.
Pierre SujobertHospices Civils de Lyon, Centre Hospitalier Lyon Sud, Laboratoire d'Hématologie, Pierre-Bénite, France.
Sarah HuetHospices Civils de Lyon, Centre Hospitalier Lyon Sud, Laboratoire d'Hématologie, Pierre-Bénite, France.
Kaddour ChabaneHospices Civils de Lyon, Centre Hospitalier Lyon Sud, Laboratoire d'Hématologie, Pierre-Bénite, France.
Evelyne Callet-BauchuHospices Civils de Lyon, Centre Hospitalier Lyon Sud, Laboratoire d'Hématologie, Pierre-Bénite, France.
Aurélie VerneyCancer Research Center of Lyon, INSERM 1052 CNRS 5286, Team "Clinical and Experimental Models of Lymphomagenesis", Faculté de Médecine et de Maïeutique Lyon-Sud Charles Mérieux, Oulins, France.
Sandrine HayetteHospices Civils de Lyon, Centre Hospitalier Lyon Sud, Laboratoire d'Hématologie, Pierre-Bénite, France.
Jean-Pierre DesvignesAix-Marseille Université, GMGF, 13385, Marseillee, France.
David SalgadoAix-Marseille Université, GMGF, 13385, Marseillee, France.
Nicolas LevyAix-Marseille Université, GMGF, 13385, Marseillee, France.
Christophe BéroudAix-Marseille Université, GMGF, 13385, Marseillee, France.
Pascale FelmanHospices Civils de Lyon, Centre Hospitalier Lyon Sud, Laboratoire d'Hématologie, Pierre-Bénite, France.
Françoise BergerCancer Research Center of Lyon, INSERM 1052 CNRS 5286, Team "Clinical and Experimental Models of Lymphomagenesis", Faculté de Médecine et de Maïeutique Lyon-Sud Charles Mérieux, Oulins, France.
Jean-Pierre MagaudHospices Civils de Lyon, Centre Hospitalier Lyon Sud, Laboratoire d'Hématologie, Pierre-Bénite, France.
Laurent GenestierCancer Research Center of Lyon, INSERM 1052 CNRS 5286, Team "Clinical and Experimental Models of Lymphomagenesis", Faculté de Médecine et de Maïeutique Lyon-Sud Charles Mérieux, Oulins, France.
Gilles SallesCancer Research Center of Lyon, INSERM 1052 CNRS 5286, Team "Clinical and Experimental Models of Lymphomagenesis", Faculté de Médecine et de Maïeutique Lyon-Sud Charles Mérieux, Oulins, France gilles.salles@chu-lyon.fr.
Alexandra Traverse-GlehenCancer Research Center of Lyon, INSERM 1052 CNRS 5286, Team "Clinical and Experimental Models of Lymphomagenesis", Faculté de Médecine et de Maïeutique Lyon-Sud Charles Mérieux, Oulins, France.
Centre National de la Recherche Scientifique · FRHôpital Lyon Sud · FRInserm · FRAix-Marseille Université · FRCentre de Recherche en Cancérologie de Lyon · FRHôpital de la Timone · FRHospices Civils de Lyon · FRUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Splenic diffuse red pulp lymphoma is an indolent small B-cell lymphoma recognized as a provisional entity in the World Health Organization 2008 classification. Its precise relationship to other related splenic B-cell lymphomas with frequent leukemic involvement or other lymphoproliferative disorders remains undetermined. We performed whole-exome sequencing to explore the genetic landscape of ten cases of splenic diffuse red pulp lymphoma using paired tumor and normal samples. A selection of 109 somatic mutations was then evaluated in a cohort including 42 samples of splenic diffuse red pulp lymphoma and compared to those identified in 46 samples of splenic marginal zone lymphoma and eight samples of hairy-cell leukemia. Recurrent mutations or losses in

Indexed as

Biomarkers, TumorGenetic VariationAgedAged, 80 and overChromosome AberrationsDNA Copy Number VariationsExome SequencingFemaleHumansKruppel-Like Transcription FactorsLeukemia, Hairy CellLymphoma, B-CellLymphoma, B-Cell, Marginal ZoneMiddle AgedMutationMyeloid Differentiation Factor 88BCOR protein, humanBiomarkers, TumorKLF2 protein, humanKruppel-Like Transcription FactorsMYD88 protein, humanMyeloid Differentiation Factor 88Proto-Oncogene ProteinsRepressor ProteinsTNFAIP3 protein, humanTumor Necrosis Factor alpha-Induced Protein 3

Identifiers

PMID28751561
PMCPMC5622860
OpenAlexW2740984018

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.