Evidence map›Paper›PMID 28751501›Full record

ArticleG3 (Bethesda, Md.)2017

Ras/MAPK Modifier Loci Revealed by eQTL in

Mark G Sterken, Linda van Bemmelen van der Plaat, Joost A G Riksen, Miriam Rodriguez, Tobias Schmid, Alex Hajnal, Jan E Kammenga, Basten L Snoek

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Plasticity of maternal environment-dependent expression-QTLs of tomato seeds.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Network Analysis PrioritizesG3 (Bethesda, Md.) · 2020
    Article
  10. Dissecting the eQTL Micro-Architecture inFrontiers in genetics · 2020
    Article
  11. WormQTL2: an interactive platform for systems genetics in Caenorhabditis elegans.Database : the journal of biological databases and curation · 2020
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Mark G SterkenLaboratory of Nematology, Wageningen University and Research, 6708PB, The Netherlands.ORCID 0000-0001-7119-6213
Linda van Bemmelen van der PlaatLaboratory of Nematology, Wageningen University and Research, 6708PB, The Netherlands.
Joost A G RiksenLaboratory of Nematology, Wageningen University and Research, 6708PB, The Netherlands.
Miriam RodriguezLaboratory of Nematology, Wageningen University and Research, 6708PB, The Netherlands.
Tobias SchmidInstitute of Molecular Life Sciences, University of Zurich, CH-8057, Switzerland.
Alex HajnalInstitute of Molecular Life Sciences, University of Zurich, CH-8057, Switzerland.ORCID 0000-0002-4098-3721
Jan E KammengaLaboratory of Nematology, Wageningen University and Research, 6708PB, The Netherlands jan.kammenga@wur.nl l.b.snoek@uu.nl.ORCID 0000-0003-4822-4436
Basten L SnoekLaboratory of Nematology, Wageningen University and Research, 6708PB, The Netherlands jan.kammenga@wur.nl l.b.snoek@uu.nl.ORCID 0000-0001-5321-2996
Wageningen University & Research · NLUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oncogenic Ras/MAPK pathway is evolutionarily conserved across metazoans. Yet, almost all our knowledge on this pathway comes from studies using single genetic backgrounds, whereas mutational effects can be highly background dependent. Therefore, we lack insight in the interplay between genetic backgrounds and the Ras/MAPK-signaling pathway. Here, we used a

Indexed as

Gene Expression RegulationQuantitative Trait LociSignal TransductionAllelesAnimalsAnimals, Genetically ModifiedCaenorhabditis elegansChromosome MappingGene Regulatory NetworksGenetic BackgroundGenetic MarkersMitogen-Activated Protein Kinasesras ProteinsGenetic MarkersMitogen-Activated Protein Kinasesras ProteinsCaenorhabditis eleganseQTLgenetic backgroundRAS/MAPK

Identifiers

PMID28751501
PMCPMC5592943
OpenAlexW2741157559

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.