Evidence map›Paper›PMID 28751444›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017

Pediatric Phase I Trial and Pharmacokinetic Study of Trebananib in Relapsed Solid Tumors, Including Primary Tumors of the Central Nervous System ADVL1115: A Children's Oncology Group Phase I Consortium Report.

Sarah E S Leary, Julie R Park, Joel M Reid, Andrew T Ralya, Sylvain Baruchel, Bing Wu, Timothy P L Roberts, Xiaowei Liu, Charles G Minard, Elizabeth Fox and 2 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. CD44/POU2F2/BCL9L axis mediates MIF-driven SPP1International journal of biological sciences · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Sarah E S LearySeattle Children's Hospital, University of Washington, Fred Hutchinson Cancer Research Center, Seattle, Washington. sarah.leary@seattlechildrens.org.
Julie R ParkSeattle Children's Hospital, University of Washington, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Joel M ReidMayo Clinic, Rochester, Minnesota.
Andrew T RalyaMayo Clinic, Rochester, Minnesota.
Sylvain BaruchelHospital for Sick Children, Toronto, Ontario.
Bing WuHospital for Sick Children, Toronto, Ontario.
Timothy P L RobertsChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Xiaowei LiuChildren's Oncology Group, Monrovia, California.
Charles G MinardDan L. Duncan Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, Texas.
Elizabeth FoxChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Brenda WeigelUniversity of Minnesota, Minneapolis, Minnesota.
Susan BlaneyTexas Children's Cancer Center, Houston, Texas.
Children's Hospital of Philadelphia · USMayo Clinic · USUniversity of Minnesota · US

Funding

Pediatric Pilot/Phase I Consortium - Foreign AccrualU01CA097452 · NCI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI BLANEY, SUSAN M. · 2002 to 2011
$28.2M
Pediatric Phase 1/Pilot ConsortiumUM1CA097452 · NCI · CHILDREN'S HOSP OF PHILADELPHIA · PI WEIGEL, BRENDA J. · 2009 to 2018
$17.7M
NCI NIH HHS U01 CA097452NCI NIH HHS UM1 CA097452
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAge FactorsAntineoplastic Agents, ImmunologicalCentral Nervous System NeoplasmsChildChild, PreschoolFemaleHumansMagnetic Resonance ImagingMaleNeoplasmsRecombinant Fusion ProteinsRecurrenceRetreatmentTreatment OutcomeYoung AdultAntineoplastic Agents, ImmunologicalRecombinant Fusion Proteinstrebananib

Identifiers

PMID28751444
PMCPMC5641249
OpenAlexW2739763269

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.