Evidence map›Paper›PMID 28750873›Full record

ArticleNeuropsychologia2017

Mnemonic function in small vessel disease and associations with white matter tract microstructure.

Athanasia Metoki, Rebecca L Brookes, Eva Zeestraten, Andrew J Lawrence, Robin G Morris, Thomas R Barrick, Hugh S Markus, Rebecca A Charlton

Abstract read
In one paragraph

Article in Neuropsychologia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. The microstructural abnormalities of cingulum was related to patients with mild cognitive impairment: a diffusion kurtosis imaging study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Article
  3. Review
  4. Observational
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Athanasia MetokiDepartment of Psychology, Goldsmiths University of London, New Cross, London SE14 6NW, United Kingdom.
Rebecca L BrookesDepartment of Clinical Neurosciences, University of Cambridge, Cambridge CB2 1TN, United Kingdom.
Eva ZeestratenInstitute of Cardiovascular and Cell Sciences, St George's University of London, Cranmer Terrace, London SW17 0RE, United Kingdom.
Andrew J LawrenceDepartment of Clinical Neurosciences, University of Cambridge, Cambridge CB2 1TN, United Kingdom.
Robin G MorrisKing's College Institute of Psychiatry, Psychology & Neuroscience, London SE5 8AF, United Kingdom.
Thomas R BarrickInstitute of Cardiovascular and Cell Sciences, St George's University of London, Cranmer Terrace, London SW17 0RE, United Kingdom.
Hugh S MarkusDepartment of Clinical Neurosciences, University of Cambridge, Cambridge CB2 1TN, United Kingdom.
Rebecca A CharltonDepartment of Psychology, Goldsmiths University of London, New Cross, London SE14 6NW, United Kingdom. Electronic address: r.charlton@gold.ac.uk.

Funding

Wellcome Trust 081589
6 · The paper itself

Abstract

Cerebral small vessel disease (SVD) is associated with deficits in working memory, with a relative sparing of long-term memory; function may be influenced by white matter microstructure. Working and long-term memory were examined in 106 patients with SVD and 35 healthy controls. Microstructure was measured in the uncinate fasciculi and cingula. Working memory was more impaired than long-term memory in SVD, but both abilities were reduced compared to controls. Regression analyses found that having SVD explained the variance in memory functions, with additional variance explained by the cingula (working memory) and uncinate (long-term memory). Performance can be explained in terms of integrity loss in specific white matter tract associated with mnemonic functions.

Indexed as

AgedAnalysis of VarianceCerebral Small Vessel DiseasesDiffusion Tensor ImagingFemaleHumansImage Processing, Computer-AssistedMaleMemory DisordersMemory, Long-TermMental Status and Dementia TestsMiddle AgedNerve Fibers, MyelinatedNeuropsychological TestsRegression AnalysisWhite MatterAgeingCingulumLong-term memorySmall vessel diseaseUncinateWorking memory

Identifiers

PMID28750873
PMCPMC5637155

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.