Evidence map›Paper›PMID 28750809›Full record

ArticleMethods in enzymology2017

Assessing Allosteric Modulation of CB

Caitlin E Scott, Debra A Kendall

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Methods in enzymology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Caitlin E ScottUniversity of Connecticut, Storrs, CT, United States.
Debra A KendallUniversity of Connecticut, Storrs, CT, United States. Electronic address: debra.kendall@uconn.edu.
University of Connecticut · US

Funding

CB1 Allosteric Modulators: Molecular, Cellular and In Vivo PharmacologyR01DA039942 · NIDA · UNIVERSITY OF CONNECTICUT STORRS · PI KINSEY, STEVEN G., LICHTMAN, ARON H · 2016 to 2020
$2.6M
NIDA NIH HHS R01 DA039942
6 · The paper itself

Abstract

The cannabinoid CB

Indexed as

Allosteric RegulationAllosteric SiteAnimalsCannabinoid Receptor AgonistsDrug Evaluation, PreclinicalExtracellular Signal-Regulated MAP KinasesHEK293 CellsHumansLigandsPhosphorylationProtein BindingProtein Processing, Post-TranslationalProtein TransportReceptor, Cannabinoid, CB1Cannabinoid Receptor AgonistsExtracellular Signal-Regulated MAP KinasesLigandsReceptor, Cannabinoid, CB1Allosteric modulatorsCannabinoid CB(1) receptorERK1/2 phosphorylationG protein-coupled receptorsG protein couplingβ-Arrestin-mediated signaling

Identifiers

PMID28750809
PMCPMC5710755
OpenAlexW2734294355

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.