Evidence map›Paper›PMID 28750627›Full record

ArticleBMC pulmonary medicine2017

Air pollution exposure is associated with MRSA acquisition in young U.S. children with cystic fibrosis.

Kevin J Psoter, Anneclaire J De Roos, Jon Wakefield, Jonathan D Mayer, Margaret Rosenfeld

Open access · goldAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Characteristics of cohort studies of long-term exposure to PMEnvironmental science and pollution research international · 2019
    Pooled it
  2. Article
  3. Sub-Toxic Exposure to DEPs and PMJournal of xenobiotics · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Fine particulate matter manipulates immune response to exacerbate microbial pathogenesis in the respiratory tract.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  9. Article
  10. Review
  11. Ethnic differences in staphylococcus aureus acquisition in cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2023
    Article
  12. Modifier Factors of Cystic Fibrosis Phenotypes: A Focus on Modifier Genes.International journal of molecular sciences · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. Indoor air pollution exposure is associated with greater morbidity in cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2022
    Article
  17. Association between insurance variability and early lung function in children with cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2022
    Observational
  18. Review
  19. Article
  20. PMJournal of environmental health science & engineering · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Kevin J PsoterDepartment of Pediatrics, School of Medicine, The Johns Hopkins University Bayview Medical Center, 5200 Eastern Ave, Mason F. Lord Bldg, Center Towers, Suite 4200, Baltimore, MD, 21224, USA. kpsoter1@jhu.edu.
Anneclaire J De RoosDepartment of Environmental and Occupational Health, Drexel University School of Public Health, Philadelphia, PA, USA.
Jon WakefieldDepartments of Biostatistics and Statistics, University of Washington, Seattle, WA, USA.
Jonathan D MayerDepartments of Epidemiology, Geography, Global Health, Medicine (Allergy and Infectious Diseases), Family Medicine, and Health Services, University of Washington, Seattle, WA, USA.
Margaret RosenfeldDivision of Pulmonary Medicine, University of Washington School of Medicine, Seattle, WA, USA.
University of Washington · USDrexel University · USJohns Hopkins Bayview Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe role of air pollution in increasing susceptibility to respiratory tract infections in the cystic fibrosis (CF) population has not been well described. We recently demonstrated that chronic PM

methodsWe conducted a retrospective study of initial acquisition of methicillin susceptible and methicillin resistant Staphylococcus aureus (MSSA and MRSA), Stenotrophomonas maltophilia and Achromobacter xylosoxidans in U.S. children <6 years of age with CF using the CF Foundation Patient Registry, 2003-2009. Multivariable Weibull regression with interval-censored outcomes was used to evaluate the association of PM

resultsDuring follow-up 63%, 17%, 24%, and 5% of children acquired MSSA, MRSA, S. maltophilia, and A. xylosoxidans, respectively. A 10 μg/m

conclusionsFine particulate matter is an independent risk factor for initial MRSA acquisition in young children with CF. These results support the increasing evidence that air pollution contributes to pulmonary morbidities in the CF community.

Indexed as

Air PollutionParticulate MatterAchromobacter denitrificansCarrier StateChildChild, PreschoolCohort StudiesCystic FibrosisEnvironmental ExposureFemaleGram-Negative Bacterial InfectionsHumansInfantMaleMethicillin-Resistant Staphylococcus aureusMultivariate AnalysisParticulate MatterAchromobacter xylosoxidansAir pollutionCystic fibrosisFine particulate matterMRSAStaphylococcus aureusStenotrophomonas maltophilia

Identifiers

PMID28750627
PMCPMC5530959
OpenAlexW2741840231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.