Evidence map›Paper›PMID 28750503›Full record

ArticleClinical and molecular hepatology2017

Protein and vitamin B6 intake are associated with liver steatosis assessed by transient elastography, especially in obese individuals.

Yvelise Ferro, Ilaria Carè, Elisa Mazza, Francesco Provenzano, Carmela Colica, Carlo Torti, Stefano Romeo, Arturo Pujia, Tiziana Montalcini

Open access · goldAbstract read
In one paragraph

Article in Clinical and molecular hepatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. From Fly to Human: Translational Relevance ofInternational journal of molecular sciences · 2026
    Review
  6. Article
  7. Review
  8. Vitamin B6 deficiency produces metabolic alterations in Drosophila.Metabolomics : Official journal of the Metabolomic Society · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Hepatoprotective Effects ofMolecules (Basel, Switzerland) · 2022
    Article
  14. Review
  15. Article
  16. Vitamin B6 and Diabetes: Relationship and Molecular Mechanisms.International journal of molecular sciences · 2020 · on this map
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Yvelise FerroDepartment of Medical and Surgical Science, Nutrition Unit, University Magna Grecia, Catanzaro, Italy.
Ilaria CarèDepartment of Medical and Surgical Science, Nutrition Unit, University Magna Grecia, Catanzaro, Italy.
Elisa MazzaDepartment of Medical and Surgical Science, Nutrition Unit, University Magna Grecia, Catanzaro, Italy.
Francesco ProvenzanoDepartment of Medical and Surgical Science, Nutrition Unit, University Magna Grecia, Catanzaro, Italy.
Carmela ColicaDepartment of Pharmacology, Consiglio Nazionale Ricerche, Istituto Scienze Neurologiche, University Magna Graecia, Catanzaro, Italy.
Carlo TortiDepartment of Medical and Surgical Science, Unit of Infectious diseases, University Magna Grecia, Catanzaro, Italy.
Stefano RomeoDepartment of Medical and Surgical Science, Nutrition Unit, University Magna Grecia, Catanzaro, Italy.
Arturo PujiaDepartment of Medical and Surgical Science, Nutrition Unit, University Magna Grecia, Catanzaro, Italy.
Tiziana MontalciniDepartment of Clinical and Experimental Medicine, Nutrition Unit, University Magna Grecia, Catanzaro, Italy.ORCID 0000-0001-7048-5830
Magna Graecia University · ITUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsAlthough the detrimental effects of several dietary components on the promotion of nonalcoholic fatty liver disease are well known, no studies have assessed the role of dietary vitamin B6. Moreover, studies on the associations between dietary components or body composition indices and liver steatosis assessed by transient elastography are rare. Our aim was to identify the nutritional factors and anthropometric parameters associated with liver steatosis.

methodsIn this cross-sectional study, we enrolled 168 individuals (35% obese) who underwent a liver steatosis assessment by Controlled Attenuation Parameter measurement and nutritional assessment.

resultsTertiles of vitamin B6 intake were positively associated with hepatic steatosis (B=1.89,

conclusionsWe found a positive association between hepatic steatosis or Controlled Attenuation Parameter score and vitamin B6/total protein intake, probably related to the high intake of meat. Vitamin B6 might have a pathogenic role related to the increase of hepatic steatosis.

Indexed as

AdultAlanine TransaminaseBlood GlucoseBody Mass IndexCross-Sectional StudiesElasticity Imaging TechniquesFeeding BehaviorFemaleHumansInterviews as TopicLogistic ModelsMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseObesityRisk FactorsAlanine TransaminaseBlood GlucoseTriglyceridesVitamin B 6ElastographyFatty liverObesityProteinsVitamin B6

Identifiers

PMID28750503
PMCPMC5628006
OpenAlexW2741333227

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.