Evidence map›Paper›PMID 28750482›Full record

ArticleJournal of mass spectrometry : JMS2017

Infrared ion spectroscopy inside a mass-selective cryogenic 2D linear ion trap.

Adam P Cismesia, Larry F Tesler, Matthew R Bell, Laura S Bailey, Nicolas C Polfer

Open access · greenAbstract read
In one paragraph

Article in Journal of mass spectrometry : JMS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Operation and Performance of a Mass-Selective Cryogenic Linear Ion Trap.Journal of the American Society for Mass Spectrometry · 2018
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Adam P CismesiaDepartment of Chemistry, University of Florida, PO Box 117200, Gainesville, FL, 32611-7200, USA.
Larry F TeslerDepartment of Chemistry, University of Florida, PO Box 117200, Gainesville, FL, 32611-7200, USA.
Matthew R BellDepartment of Chemistry, University of Florida, PO Box 117200, Gainesville, FL, 32611-7200, USA.
Laura S BaileyDepartment of Chemistry, University of Florida, PO Box 117200, Gainesville, FL, 32611-7200, USA.
Nicolas C PolferDepartment of Chemistry, University of Florida, PO Box 117200, Gainesville, FL, 32611-7200, USA.ORCID http://orcid.org/0000-0002-5892-8667
University of Florida · US

Funding

Infrared laser spectroscopy of mass-separated metabolitesR01GM110077 · NIGMS · UNIVERSITY OF FLORIDA · PI ROITBERG, ADRIAN ENRIQUE · 2014 to 2017
$926k
NIGMS NIH HHS R01 GM110077
6 · The paper itself

Abstract

We demonstrate operation of the first cryogenic 2D linear ion trap (LIT) with mass-selective capabilities. This trap presents a number of advantages for infrared ion "action" spectroscopy studies, particularly those employing the "tagging/messenger" spectroscopy approach. The high trapping efficiencies, trapping capacities, and low detection limits make 2D LITs a highly suitable choice for low-concentration analytes from scarce biological samples. In our trap, ions can be cooled down to cryogenic temperatures to achieve higher-resolution infrared spectra, and individual ions can be mass selected prior to irradiation for a background-free photodissociation scheme. Conveniently, multiple tagged analyte ions can be mass isolated and efficiently irradiated in the same experiment, allowing their infrared spectra to be recorded in parallel. This multiplexed approach is critical in terms of increasing the duty cycle of infrared ion spectroscopy, which is currently a key weakness of the technique. The compact design of this instrument, coupled with powerful mass selection capabilities, set the stage for making cryogenic infrared ion spectroscopy viable as a bioanalytical tool in small molecule identification.

Indexed as

cryogenicion spectroscopylinear ion traptaggingvibrational spectroscopy

Identifiers

PMID28750482
PMCPMC5690808
OpenAlexW2740491624

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.