Evidence map›Paper›PMID 28750223›Full record

ArticleEnvironment international2017

Associations between flame retardant applications in furniture foam, house dust levels, and residents' serum levels.

Stephanie C Hammel, Kate Hoffman, Amelia M Lorenzo, Albert Chen, Allison L Phillips, Craig M Butt, Julie Ann Sosa, Thomas F Webster, Heather M Stapleton

Open access · greenAbstract read
In one paragraph

Article in Environment international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 82 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Children's exposure to brominated flame retardants in the home: The TESIE study.Environmental pollution (Barking, Essex : 1987) · 2024
    Article
  7. Article
  8. Investigation ofCurrent research in toxicology · 2024
    Article
  9. Article
  10. Article
  11. UsingFrontiers in toxicology · 2023
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Environmental Chemicals Altered in Association With Deployment for High Risk Areas.Journal of occupational and environmental medicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Stephanie C HammelNicholas School of the Environment, Duke University, Durham, NC, United States. Electronic address: stephanie.hammel@duke.edu.
Kate HoffmanNicholas School of the Environment, Duke University, Durham, NC, United States. Electronic address: kate.hoffman@duke.edu.
Amelia M LorenzoNicholas School of the Environment, Duke University, Durham, NC, United States. Electronic address: amelia.lorenzo@duke.edu.
Albert ChenNicholas School of the Environment, Duke University, Durham, NC, United States.
Allison L PhillipsNicholas School of the Environment, Duke University, Durham, NC, United States. Electronic address: allison.l.phillips@duke.edu.
Craig M ButtNicholas School of the Environment, Duke University, Durham, NC, United States.
Julie Ann SosaDepartment of Surgery, Duke Cancer Institute, and Duke Clinical Research Institute, Duke University, Durham, NC, United States. Electronic address: julie.sosa@dm.duke.edu.
Thomas F WebsterBoston University School of Public Health, Boston University, Boston, MA, United States. Electronic address: twebster@bu.edu.
Heather M StapletonNicholas School of the Environment, Duke University, Durham, NC, United States. Electronic address: heather.stapleton@duke.edu.
Duke University · USBoston University · USClinical Research Institute · US

Funding

Zebrafish as a Detector of Organophosphate ExposureP42ES010356 · NIEHS · DUKE UNIVERSITY · PI EDWARD D LEVIN · 2000 to 2026
$56.2M
Children's Exposure to Flame Retardants: Effects on Thyroid Hormone RegulationR01ES016099 · NIEHS · DUKE UNIVERSITY · PI STAPLETON, HEATHER M · 2008 to 2017
$5.0M
NIEHS NIH HHS P42 ES010356NIEHS NIH HHS R01 ES016099
6 · The paper itself

Abstract

Polyurethane foam (PUF) in upholstered furniture frequently is treated with flame retardant chemicals (FRs) to reduce its flammability and adhere to rigorous flammability standards. For decades, a commercial mixture of polybrominated diphenyl ethers (PBDEs) called PentaBDE was commonly applied to foam to fulfill these regulations; however, concerns over toxicity, bioaccumulation, and persistence led to a global phase-out in the mid-2000s. Although PentaBDE is still detected in older furniture, other FR compounds such as tris(1,3-dichloroisopropyl) phosphate (TDCIPP) and Firemaster® 550 (FM550) have been increasingly used as replacements. While biomonitoring studies suggest exposure is widespread, the primary sources of exposure are not clearly known. Here, we investigated the relationships between specific FR applications in furniture foam and human exposure. Paired samples of furniture foam, house dust and serum samples were collected from a cohort in North Carolina, USA and analyzed for FRs typically used in PUF. In general, the presence of a specific FR in the sofa of a home was associated with an increase in the concentration of that FR in house dust. For example, the presence of PentaBDE in sofas was associated with significantly higher levels of BDE-47, a major component of PentaBDE, in house dust (10

Indexed as

Interior Design and FurnishingsPolyurethanesCohort StudiesDustEnvironmental MonitoringEnvironmental PollutantsFemaleFlame RetardantsHalogenated Diphenyl EthersHumansMaleMiddle AgedNorth CarolinaOrganophosphatesOrganophosphorus CompoundsPolybrominated BiphenylsDustEnvironmental PollutantsFiremaster 550Flame RetardantsHalogenated Diphenyl EthersOrganophosphatesOrganophosphorus CompoundsPolybrominated Biphenylspolyurethane foamPolyurethanestri-(2-chloroisopropyl)phosphateBrominated flame retardantsExposureHouse dustPolyurethane foamSerum biomarkers

Identifiers

PMID28750223
PMCPMC5572835
OpenAlexW2737023264

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.