Evidence map›Paper›PMID 28749970›Full record

SynthesisPloS one2017

Effectiveness of physical activity on patients with depression and Parkinson's disease: A systematic review.

Pei-Ling Wu, Megan Lee, Tzu-Ting Huang

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06246747 (The Use of Telerehabilitation to Improve Movement-related Outcomes and Quality of Life for Patients With Parkinson's Disease), which is not on this map. Cited by 98 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 15 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06246747 nacompletednot on this mapstarted 2020, after this paper: background citation

The Use of Telerehabilitation to Improve Movement-related Outcomes and Quality of Life for Patients With Parkinson's Disease: A Pilot Randomized Controlled Trial

TypeinterventionalSponsorWizecareRan2020 to 2023Enrolled19ConditionsParkinson DiseaseArmsIn clinic physical therapy, Telerehabilitation only
3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 15 syntheses or guidelines pooled it.

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  12. Physical Activity during COVID-19 Lockdown in Italy: A Systematic Review.International journal of environmental research and public health · 2021
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  16. The effects of dual-task training with different task priorities on physical performance and cognitive status in patients with Parkinson's disease: a single-blind, randomized controlled trial.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pei-Ling WuGraduate Institute of Clinical Medical Sciences, Nursing, Chang Gung University, Tao-Yuan, Taiwan.
Megan LeeDepartment of biochemistry, University of Washington, Seattle, WA, United States of America.
Tzu-Ting HuangHealthy Aging Research Center School of Nursing, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan.ORCID http://orcid.org/0000-0002-1288-6545

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimIn this paper we aimed to systematically review the literature on physical activity's effect on depressive symptoms in Parkinson disease.

backgroundDepression is a common symptom of Parkinson's disease and is associated with increased disability, rapid progression of motor symptoms, mortality, and adverse effects on Quality of Life.

designA systematic review of primary research was undertaken and conducted according to the Preferred Reporting Items for Systematic Reviews. DATA SOURCES: Databases Scopus, Psycho-info, CINAHL, PubMed, and ProQuest Cochrance were searched from January 2006 to June 2017. The language was restricted to English. REVIEW

methodsAbstracts were screened and reviewed against the eligibility criteria (participants' mean age were ≥ 60 with PD, PA interventions, depression as one of outcome variables, and Randomized Control Trail or quasi-experimental design). Two reviewers appraised the quality of the data extracted. The modified Jadad scale assessed the quality of the methodology of the published papers.

resultsThe database search yielded 769 abstracts, 11 of which were included in this review and awarded scores ranging from 3 to 8 (Scale scores range from 0 to 8 points, higher scores indicated better quality) by the raters. These 11 studies included 342 patients and executed 17 kinds of physical activity programs. Results of this review show empirical evidence to support the efficacy of physical activity for the population with Parkinson's disease. Aerobic training exercise significantly improved the participants' scores on the Unified Parkinson's Disease Rating Scale, the Beck Depression Inventory, and the Quality of Life of the patients. Qigong improved scores in UPDRS-III and decreased incidences of multiple non-motor symptoms and depression. Furthermore, a balance-training program, such as Tai Chi, can improve postural stability and Quality of Life.

conclusionsPhysical activity may assuage the degeneration of motor skills and depression as well as increase the Quality of Life of Parkinson's disease patients, with aerobic training producing the best results. These findings suggest that physical activity, notably aerobic training, could be a good exercise strategy for patients with Parkinson's disease.

Indexed as

ExerciseAnxietyDepressionHumansParkinson DiseaseQuality of LifeTreatment Outcome

Identifiers

PMID28749970
PMCPMC5531507

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.