Evidence map›Paper›PMID 28749481›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2017

Evaluation of critical congenital heart defects screening using pulse oximetry in the neonatal intensive care unit.

K Van Naarden Braun, R Grazel, R Koppel, S Lakshminrusimha, J Lohr, P Kumar, B Govindaswami, M Giuliano, M Cohen, N Spillane and 11 more

Open access · hybridAbstract readEvaluation StudyMulticenter Study
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 18 institutions in 1 country.

K Van Naarden BraunNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, USA.
R GrazelNew Jersey Department of Health, Trenton, NJ, USA.
R KoppelLong Island Jewish Cohen Children's Medical Center, New Hyde Park, NY, USA.
S LakshminrusimhaUniversity of Buffalo Medical Center, Buffalo, NY, USA.
J LohrUniversity of Minnesota Medical System, Minneapolis, MN, USA.
P KumarUniversity of Illinois Medical Center, Peoria, IL, USA.
B GovindaswamiSanta Clara Valley Medical Center, San Jose, CA, USA.
M GiulianoHackensack University Medical Center, Hackensack, NJ, USA.
M CohenChildren's Hospital of New Jersey at Newark Beth Israel Medical Center, Newark, NJ, USA.
N SpillaneHackensack University Medical Center, Hackensack, NJ, USA.ORCID 0000-0002-9689-0743
P JegatheesanSanta Clara Valley Medical Center, San Jose, CA, USA.
D McClureSaint Joseph's Regional Medical Center, Paterson, NJ, USA.
D HassingerMorristown Medical Center, Morristown, NJ, USA.
O FofahRutgers New Jersey Medical School, Newark, NJ, USA.ORCID 0000-0001-8883-5341
S ChandraSaint Peter's University Hospital, New Brunswick, NJ, USA.
D AllenSaint Peter's University Hospital, New Brunswick, NJ, USA.
R AxelrodCapital Health Medical Center Hopewell, Pennington, NJ, USA.
J BlauNorthwell Staten Island University Hospital, Staten Island, NY, USA.ORCID 0000-0002-8115-0697
S HudomeMonmouth Medical Center, Long Branch, NJ, USA.
E AssingJersey Shore University Medical Center, Neptune, NJ, USA.
L F GargNew Jersey Department of Health, Trenton, NJ, USA.
Hackensack University Medical Center · USSaint Peter's University Hospital · USSanta Clara Valley Medical Center · USAmerican Academy of Pediatrics · USBuffalo VA Medical Center · USCapital Health Medical Center Hopewell · USCenters for Disease Control and Prevention · USJersey Shore University Medical Center · USLong Island Jewish Medical Center · USMonmouth Medical Center · USMorristown Medical Center · USNewark Beth Israel Medical Center · USNew Jersey Department of Health · USPeoria campus of the University of Illinois System · USRutgers, The State University of New Jersey · USStaten Island University Hospital · USSt. Joseph’s University Medical Center · USUniversity of Minnesota System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the implementation of early screening for critical congenital heart defects (CCHDs) in the neonatal intensive care unit (NICU) and potential exclusion of sub-populations from universal screening. STUDY

designProspective evaluation of CCHD screening at multiple time intervals was conducted in 21 NICUs across five states (n=4556 infants).

resultsOf the 4120 infants with complete screens, 92% did not have prenatal CHD diagnosis or echocardiography before screening, 72% were not receiving oxygen at 24 to 48 h and 56% were born ⩾2500 g. Thirty-seven infants failed screening (0.9%); none with an unsuspected CCHD. False positive rates were low for infants not receiving oxygen (0.5%) and those screened after weaning (0.6%), yet higher among infants born at <28 weeks (3.8%). Unnecessary echocardiograms were minimal (0.2%).

conclusionGiven the majority of NICU infants were ⩾2500 g, not on oxygen and not preidentified for CCHD, systematic screening at 24 to 48 h may be of benefit for early detection of CCHD with minimal burden.

Indexed as

OximetryEchocardiographyGestational AgeHeart Defects, CongenitalHumansInfant, Extremely Low Birth WeightInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalNeonatal ScreeningOxygen Inhalation TherapyProspective Studies

Identifiers

PMID28749481
PMCPMC5633653
OpenAlexW2741856696

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.