ArticleMolecules (Basel, Switzerland)2017
Distinct Mechanisms of Biotic and Chemical Elicitors Enable Additive Elicitation of the Anticancer Phytoalexin Glyceollin I.
Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
- An Integrated Transient Expression and UPLC-PDA Approach for Functional Genomics and Metabolic Analysis of Cannabis sativa.Biotechnology journal · 2026Article
- The WRKY Family Transcription Factor GmWRKY72 Represses Glyceollin Phytoalexin Biosynthesis in Soybean.Plants (Basel, Switzerland) · 2024Article
- Genetic basis and selection of glyceollin elicitation in wild soybean.Frontiers in plant science · 2024Article
- RNA-Seq Dissects Incomplete Activation of Phytoalexin Biosynthesis by the Soybean Transcription Factors GmMYB29A2 and GmNAC42-1.Plants (Basel, Switzerland) · 2023Article
- Elicitation of Roots and AC-DC with PEP-13 Peptide Shows Differential Defense Responses in Multi-Omics.Cells · 2022Article
- Glyceollin Transcription Factor GmMYB29A2 Regulates Soybean Resistance toPlant physiology · 2020Article
- Elicitor and Receptor Molecules: Orchestrators of Plant Defense and Immunity.International journal of molecular sciences · 2020Review
- The NAC family transcription factor GmNAC42-1 regulates biosynthesis of the anticancer and neuroprotective glyceollins in soybean.BMC genomics · 2019Article
- An Update on the Effects of Glyceollins on Human Health: Possible Anticancer Effects and Underlying Mechanisms.Nutrients · 2019Review
- Transcriptional and Chemical Changes in Soybean Leaves in Response to Long-Term Aphid Colonization.Frontiers in plant science · 2019Article
- Acidity stress for the systemic elicitation of glyceollin phytoalexins in soybean plants.Plant signaling & behavior · 2019Article
- Combining semi-synthesis with plant and microbial biocatalysis: new frontiers in producing a chemical arsenal against cancer.RSC advances · 2018Article
- Hormone deficient mutants have distinct flavonoid proportion fingerprints in response to abiotic stress.Plant signaling & behavior · 2018Article
- Structure, Chemical Analysis, Biosynthesis, Metabolism, Molecular Engineering, and Biological Functions of Phytoalexins.Molecules (Basel, Switzerland) · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phytoalexins are metabolites biosynthesized in plants in response to pathogen, environmental, and chemical stresses that often have potent bioactivities, rendering them promising for use as therapeutics or scaffolds for pharmaceutical development. Glyceollin I is an isoflavonoid phytoalexin from soybean that exhibits potent anticancer activities and is not economical to synthesize. Here, we tested a range of source tissues from soybean, in addition to chemical and biotic elicitors, to understand how to enhance the bioproduction of glyceollin I. Combining the inorganic chemical silver nitrate (AgNO₃) with the wall glucan elicitor (WGE) from the soybean pathogen
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