ArticleEnvironmental health perspectives2017
Genome-wide Association Study of Susceptibility to Particulate Matter-Associated QT Prolongation.
Article in Environmental health perspectives, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- A large genome-wide association study of QT interval length utilizing electronic health records.Genetics · 2022Pooled it
- Protein prediction for trait mapping in diverse populations.PloS one · 2022Article
- Gene-Environment Interactions for Cardiovascular Disease.Current atherosclerosis reports · 2021Review
- Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation.Environment international · 2019Article
- Case-crossover analysis of short-term particulate matter exposures and stroke in the health professionals follow-up study.Environment international · 2019Article
- Genome-wide Association Study of Susceptibility to Particulate Matter-Associated QT Prolongation.Environmental health perspectives · 2017Article
Corrections and comments
- Erratum issued
Authors and funding
17 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundAmbient particulate matter (PM) air pollution exposure has been associated with increases in QT interval duration (QT). However, innate susceptibility to PM-associated QT prolongation has not been characterized.
objectiveTo characterize genetic susceptibility to PM-associated QT prolongation in a multi-racial/ethnic, genome-wide association study (GWAS).
methodsUsing repeated electrocardiograms (1986–2004), longitudinal data on PM<10 μm in diameter (PM
resultsA common variant (rs1619661; coded allele:
conclusionsThe findings suggest that biologically plausible genetic factors may alter susceptibility to PM
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.