Evidence map›Paper›PMID 28749360›Full record

ArticleIEEE journal of biomedical and health informatics2018

Multi-Hypergraph Learning for Incomplete Multimodality Data.

Mingxia Liu, Yue Gao, Pew-Thian Yap, Dinggang Shen

Abstract read
In one paragraph

Article in IEEE journal of biomedical and health informatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Improving Late-Life Depression Analysis with Collaborative Domain Adaptation: Learning from Heterogeneous Structural MRI.Reconstruction and imaging motion estimation, and graphs in biomedical image analysis : first international workshop, RIME 2025 and 7th international workshop, GRAIL 2025, Daejeon, South Korea, September 27, 2025 : proceedings. RIME (Wo... · 2026
    Article
  3. GAMMA-PD: Graph-based Analysis of Multi-Modal Motor Impairment Assessments in Parkinson's Disease.Graphs in biomedical image analysis : 6th International Workshop, GRAIL 2024, held in conjunction with MICCAI 2024, Marrakesh, Morocco, October 6, 2024, Proceedings. GRAIL (Workshop) (6th : 2024 : Marrakesh, Morocco) · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Deep learning methods and applications in neuroimaging.Journal of neuroscience methods · 2020
    Article
  8. Article
  9. Synthesizing Missing PET from MRI with Cycle-consistent Generative Adversarial Networks for Alzheimer's Disease Diagnosis.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mingxia Liu
Yue Gao
Pew-Thian Yap
Dinggang Shen

Funding

UC Davis Alzheimer's Disease Core CenterP30AG010129 · NIA · UNIVERSITY OF CALIFORNIA DAVIS · PI DECARLI, CHARLES · 1991 to 2020
$28.3M
Longitudinal Mapping of Human Brain Development in the First Years of LifeR01EB008374 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2009 to 2024
$5.1M
Development of Robust Brain Measurement Tools Informed by Ultrahigh Field 7T MRIR01EB006733 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2008 to 2020
$4.5M
Quantifying Brain Abnormality by Multimodality Neuroimage Analysis,R01AG041721 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, MINGXIA · 2012 to 2019
$3.0M
Infant Brain Measurement and Super-Resolution Atlas ConstructionR01MH100217 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SHEN, DINGGANG · 2013 to 2016
$2.3M
Assessing Large-scale Brain Connectivities in Mild Cognitive ImpairmentR01AG042599 · NIA · UNIVERSITY OF GEORGIA · PI LIU, TIANMING · 2013 to 2017
$1.4M
Fast, Robust Analysis of Large Population DataR01EB009634 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SHEN, DINGGANG · 2011 to 2014
$1.3M
Diagnosis of Alzheimer's Disease Using Dynamic High-Order Brain NetworksR01EB022880 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2016 to 2018
$1.1M
"MR Morphometrics and Cognitive Decline Rate in Large-Scale Aging Studies"K01AG030514 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CARMICHAEL, OWEN T. · 2008 to 2012
$495k
NIA NIH HHS K01 AG030514NIA NIH HHS P30 AG010129NIA NIH HHS R01 AG041721NIA NIH HHS R01 AG042599NIBIB NIH HHS R01 EB006733NIBIB NIH HHS R01 EB008374NIBIB NIH HHS R01 EB009634NIBIB NIH HHS R01 EB022880NIMH NIH HHS R01 MH100217
6 · The paper itself

Abstract

Multi-modality data convey complementary information that can be used to improve the accuracy of prediction models in disease diagnosis. However, effectively integrating multi-modality data remains a challenging problem, especially when the data are incomplete. For instance, more than half of the subjects in the Alzheimer's disease neuroimaging initiative (ADNI) database have no fluorodeoxyglucose positron emission tomography and cerebrospinal fluid data. Currently, there are two commonly used strategies to handle the problem of incomplete data: 1) discard samples having missing features; and 2) impute those missing values via specific techniques. In the first case, a significant amount of useful information is lost and, in the second case, additional noise and artifacts might be introduced into the data. Also, previous studies generally focus on the pairwise relationships among subjects, without considering their underlying complex (e.g., high-order) relationships. To address these issues, in this paper, we propose a multi-hypergraph learning method for dealing with incomplete multimodality data. Specifically, we first construct multiple hypergraphs to represent the high-order relationships among subjects by dividing them into several groups according to the availability of their data modalities. A hypergraph regularized transductive learning method is then applied to these groups for automatic diagnosis of brain diseases. Extensive evaluation of the proposed method using all subjects in the baseline ADNI database indicates that our method achieves promising results in AD/MCI classification, compared with the state-of-the-art methods.

Indexed as

AlgorithmsAgedAged, 80 and overAlzheimer DiseaseBrainDatabases, FactualFemaleHumansImage Interpretation, Computer-AssistedMaleMultimodal Imaging

Identifiers

PMID28749360
PMCPMC5785578

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.