ArticleEuropean journal of preventive cardiology2017
Validation and recalibration of the Framingham cardiovascular disease risk models in an Australian Indigenous cohort.
Article in European journal of preventive cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Discrimination and calibration performances of non-laboratory-based and laboratory-based cardiovascular risk predictions: a systematic review.Open heart · 2025Pooled it
- Economic Modelling of Chronic Kidney Disease: A Systematic Literature Review to Inform Conceptual Model Design.PharmacoEconomics · 2019Pooled it
- Modified Sleep Apnea Severity Index and Cardiovascular Risk in CPAP-Intolerant OSA Patients.The Laryngoscope · 2026Article
- Diagnostic Accuracy of Cardiovascular Disease Prediction Models: A Systematic Review and Meta-Analysis of Validation Studies.Health science reports · 2026Review
- Innovations In Artificial Intelligence-Guided Atherosclerosis Cardiovascular Imaging: From Detection to Prognosis.Current atherosclerosis reports · 2026Review
- Diversity and Representation in Cardiovascular Research: Evidence Gaps, Emerging Models, and Policy Implications.International journal of environmental research and public health · 2026Review
- An exploratory analysis of the utility of maximum degree of stenosis on computed tomography coronary angiography for predicting major adverse cardiac events.BMC medical imaging · 2025Article
- Against reflexive recalibration: towards a causal framework for addressing miscalibration.Diagnostic and prognostic research · 2025Article
- Impact of Race on Classification of Atherosclerotic Risk Using a National Cardiovascular Risk Prediction Tool.AJPM focus · 2024Article
- Recalibration of Framingham risk for a local population of Sri Lanka.BMC public health · 2024Article
- Systematic review of Internet of medical things for cardiovascular disease prevention among Australian first nations.Heliyon · 2023Review
- Evidence supporting the choice of a new cardiovascular risk equation for Australia.The Medical journal of Australia · 2023Review
- Erratum: Potentially preventable dementia in a First Nations population in the Torres Strait and Northern Peninsula Area of North Queensland, Australia: a cross sectional analysis using population attributable fractions.The Lancet regional health. Western Pacific · 2023Article
- Predicted cardiovascular disease risk and prescribing of antihypertensive therapy among patients with hypertension in Australia using MedicineInsight.Journal of human hypertension · 2023Article
- Potentially preventable dementia in a First Nations population in the Torres Strait and Northern Peninsula Area of North Queensland, Australia: A cross sectional analysis using population attributable fractions.The Lancet regional health. Western Pacific · 2022Article
- Using Health Check Data to Understand Risks for Dementia and Cognitive Impairment Among Torres Strait Islander and Aboriginal Peoples in Northern Queensland-A Data Linkage Study.Frontiers in public health · 2022Article
- The Oral, Gut Microbiota and Cardiometabolic Health of Indigenous Orang Asli Communities.Frontiers in cellular and infection microbiology · 2022Article
- Predictive Ability of a Clinical-Genetic Risk Score for Venous Thromboembolism in Northern and Southern European Populations.TH open : companion journal to thrombosis and haemostasis · 2021Article
- National Heart Foundation of Australia: position statement on coronary artery calcium scoring for the primary prevention of cardiovascular disease in Australia.The Medical journal of Australia · 2021Article
- Risk prediction models for atherosclerotic cardiovascular disease: A systematic assessment with particular reference to Qatar.Qatar medical journal · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background In Australia, clinical guidelines for primary prevention of cardiovascular disease recommend the use of the Framingham model to help identify those at high risk of developing the disease. However, this model has not been validated for the Indigenous population. Design Cohort study. Methods Framingham models were applied to the Well Person's Health Check (WPHC) cohort (followed 1998-2014), which included 1448 Aboriginal and Torres Strait Islanders from remote Indigenous communities in Far North Queensland. Cardiovascular disease risk predicted by the original and recalibrated Framingham models were compared with the observed risk in the WPHC cohort. Results The observed five- and 10-year cardiovascular disease probability of the WPHC cohort was 10.0% (95% confidence interval (CI): 8.5-11.7) and 18.7% (95% CI: 16.7-21.0), respectively. The Framingham models significantly underestimated the cardiovascular disease risk for this cohort by around one-third, with a five-year cardiovascular disease risk estimate of 6.8% (95% CI: 6.4-7.2) and 10-year risk estimates of 12.0% (95% CI: 11.4-12.6) and 14.2% (95% CI: 13.5-14.8). The original Framingham models showed good discrimination ability (C-statistic of 0.67) but a significant lack of calibration (χ
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.