ArticleThe British journal of radiology2017
Quantifying potential reduction in contrast dose with monoenergetic images synthesized from dual-layer detector spectral CT.
Article in The British journal of radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Guideline on the use of iodinated contrast media in patients with kidney disease 2018.Clinical and experimental nephrology · 2020Guideline
- Automatic spectral imaging protocol and iterative reconstruction for radiation dose reduction in typical hepatic hemangioma computed tomography with reduced iodine load: a preliminary study.The British journal of radiology · 2018Trial
- Contrast medium dose optimization in the era of multi-energy CT.Japanese journal of radiology · 2025Review
- Photon-counting detector CT angiography to evaluate carotid and subclavian artery stents and compared to ultrasound and angiography - an in-vivo study with spectral reconstructions.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Contrast Volume Reduction in Oncologic Body Imaging Using Dual-Energy CT: A Comparison with Single-Energy CT.Diagnostics (Basel, Switzerland) · 2025Article
- Standardizing technical parameters and terms for abdominopelvic photon-counting CT: laying the groundwork for innovation and evidence sharing.Abdominal radiology (New York) · 2024Review
- An adult and pediatric size-based contrast administration reduction phantom study for single and dual-energy CT through preservation of contrast-to-noise ratio.Journal of applied clinical medical physics · 2024Article
- Feasibility of Reduced Iodine Loads for Vascular Assessment Prior to Transcatheter Aortic Valve Implantation (TAVI) Using Spectral Detector CT.Diagnostics (Basel, Switzerland) · 2024Article
- Feasibility of using 8 mL of iodinated contrast media in cerebral computed tomographic angiography with a dual-layer spectral detector.Quantitative imaging in medicine and surgery · 2024Article
- Pros and Cons of Dual-Energy CT Systems: "One Does Not Fit All".Tomography (Ann Arbor, Mich.) · 2023Review
- Utilisation of virtual non-contrast images and virtual mono-energetic images acquired from dual-layer spectral CT for renal cell carcinoma: image quality and radiation dose.Insights into imaging · 2022Article
- Spectral CT of the abdomen: Where are we now?Insights into imaging · 2021Review
- New advances in CT imaging of pancreas diseases: a narrative review.Gland surgery · 2020Review
- Guideline on the use of iodinated contrast media in patients with kidney disease 2018.Japanese journal of radiology · 2020Article
- Renal cystic lesions characterization using spectral detector CT (SDCT): Added value of spectral results.The British journal of radiology · 2019Article
- Myocardial Late Iodine Enhancement and Extracellular Volume Quantification with Dual-Layer Spectral Detector Dual-Energy Cardiac CT.Radiology. Cardiothoracic imaging · 2019Article
- Contrast agent concentration optimization in CTA using low tube voltage and dual-energy CT in multiple vendors: a phantom study.The international journal of cardiovascular imaging · 2018Article
- Reduced iodinated contrast media for abdominal imaging by dual-layer spectral detector computed tomography for patients with kidney disease.Radiology case reports · 2018Article
- Dual-layer DECT for multiphasic hepatic CT with 50 percent iodine load: a matched-pair comparison with a 120 kVp protocol.European radiology · 2018Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo estimate the potential dose reduction in iodinated contrast when interpreting monoenergetic images from spectral CT.
methods51 paediatric patients received contrast-enhanced CT simulation for radiation therapy using a single-source, dual-layer detector spectral CT. The contrast-to-noise ratios (CNRs) of blood vessels were measured relative to surrounding soft tissue. CNRs on monoenergetic 40-70 keV images were compared with polychromatic 120 kVp images. To compare with in vivo results, a phantom with iodine inserts (2-20 mg ml
resultsMonoenergetic keV and body site had significant effects on CNR ratio (p < 0.0001). Across all body sites, the mean CNR ratio (monoenergetic/polychromatic CNR) was 3.3 (20
conclusion50 keV monoenergetic images provided the best balance of improved CNR on all studies (mean 2.4-fold increase in vivo) for enhancing vessels vs image noise. A 50% reduction in contrast dose on a 50 keV image should maintain comparable or better CNR as compared with polychromatic CT in over 80% of CT studies. Advances in knowledge: Use of a novel, single-source, dual-layer detector spectral CT scanner to improve visualization of contrast-enhanced blood vessels will reduce the amount of iodinated contrast required for radiation oncology treatment planning.
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