Evidence map›Paper›PMID 28749174›Full record

ReviewThe British journal of radiology2017

Microbeam radiation therapy - grid therapy and beyond: a clinical perspective.

Elisabeth Schültke, Jacques Balosso, Thomas Breslin, Guido Cavaletti, Valentin Djonov, Francois Esteve, Michael Grotzer, Guido Hildebrandt, Alexander Valdman, Jean Laissue

Abstract readReview
In one paragraph

Review in The British journal of radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Partial-Volume Irradiation of Murine Tumors.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Elisabeth Schültke1 Department of Radiooncology, Rostock University Medical Center, Rostock, Germany.
Jacques Balosso2 Departement of Radiation Oncology and Medical Physics, University Grenoble Alpes (UGA) and Centre Hospitalier Universitaire Grenoble Alpes (CHUGA), Grenoble, France.
Thomas Breslin3 Department of Oncology, Clinical Sciences, Lund University, Lund, Sweden.
Guido Cavaletti5 Experimental Neurology Unit and Milan Center for Neuroscience, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Valentin Djonov6 Institute of Anatomy, University of Bern, Bern, Switzerland.
Francois Esteve2 Departement of Radiation Oncology and Medical Physics, University Grenoble Alpes (UGA) and Centre Hospitalier Universitaire Grenoble Alpes (CHUGA), Grenoble, France.
Michael Grotzer7 Department of Oncology, University Children's Hospital of Zurich, Zurich, Switzerland.
Guido Hildebrandt1 Department of Radiooncology, Rostock University Medical Center, Rostock, Germany.
Alexander Valdman8 Department of Oncology and Pathology, Karolinska University Hospital, Stockholm, Sweden.
Jean Laissue6 Institute of Anatomy, University of Bern, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbeam irradiation is spatially fractionated radiation on a micrometer scale. Microbeam irradiation with therapeutic intent has become known as microbeam radiation therapy (MRT). The basic concept of MRT was developed in the 1980s, but it has not yet been tested in any human clinical trial, even though there is now a large number of animal studies demonstrating its marked therapeutic potential with an exceptional normal tissue sparing effect. Furthermore, MRT is conceptually similar to macroscopic grid based radiation therapy which has been used in clinical practice for decades. In this review, the potential clinical applications of MRT are analysed for both malignant and non-malignant diseases.

Indexed as

Radiation Dose HypofractionationHumansNeoplasmsRadiotherapy

Identifiers

PMID28749174
PMCPMC5853350

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.