Evidence map›Paper›PMID 28749013›Full record

ArticleThe Journal of physiology2017

Physiological vs. pharmacological signalling to myosin phosphorylation in airway smooth muscle.

Ning Gao, Ming-Ho Tsai, Audrey N Chang, Weiqi He, Cai-Ping Chen, Minsheng Zhu, Kristine E Kamm, James T Stull

Abstract read
In one paragraph

Article in The Journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ning GaoDepartment of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Ming-Ho TsaiDepartment of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Audrey N ChangDepartment of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Weiqi HeModel Animal Research Center and MOE Key Laboratory of Model Animal for Disease Study, Nanjing University, Nanjing, China.
Cai-Ping ChenModel Animal Research Center and MOE Key Laboratory of Model Animal for Disease Study, Nanjing University, Nanjing, China.
Minsheng ZhuModel Animal Research Center and MOE Key Laboratory of Model Animal for Disease Study, Nanjing University, Nanjing, China.
Kristine E KammDepartment of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
James T StullDepartment of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-2993-7206

Funding

Pathology and Molecular Imaging CoreP01HL110869 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MILEWICZ, DIANNA M · 2012 to 2016
$10.4M
NHLBI NIH HHS P01 HL110869
6 · The paper itself

Abstract

key pointsSmooth muscle myosin regulatory light chain (RLC) is phosphorylated by Ca ABSTRACT: Ca

Indexed as

Signal TransductionAnimalsCarbacholCattleCells, CulturedCholinergic AgonistsMaleMiceMice, Inbred C57BLMyocytes, Smooth MuscleMyosin-Light-Chain PhosphataseMyosin Light ChainsPhosphorylationProtein Phosphatase 1Protein Processing, Post-TranslationalTracheaCarbacholCholinergic AgonistsMbs85 protein, mouseMyosin-Light-Chain PhosphataseMyosin Light ChainsPpp1r12a protein, mouseProtein Phosphatase 1airway smooth musclecontractionmyosin light chain kinasemyosin light chain phosphatasemyosin regulatory light chain phosphorylation

Identifiers

PMID28749013
PMCPMC5621497

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.